Umgubo weAzelaic acid , njengendalo egcwele i-dicarboxylic acid, itsale ingqalelo enkulu kwiimveliso zokhathalelo lwesikhumba kwiminyaka yakutshanje. Ukongeza kwiimpembelelo zayo ezibalulekileyo ekuphatheni i-acne kunye nokulawula umbala webala, i-azelaic acid ibonisa ezinye iimpawu eziphawulekayo. Njenge-antioxidant, inokunceda ulusu ukulwa nomonakalo omkhulu, ukugcina impilo yesikhumba kunye nobutsha. Ukongeza, i-azelaic acid ibonakaliswe ukuba ineempembelelo ezichasayo kwaye inokunciphisa ukudumba kwesikhumba, iyenze ilungele abantu abanolusu olubuthathaka kunye neentlobo zolusu ezithanda ukubomvu. Ubume bayo obukhethekileyo bemolekyuli buyenza ibe ntle kakhulu ekulawuleni ibala lesikhumba kunye nokuphucula ithoni yesikhumba engalinganiyo. Ngokubanzi, i-azelaic acid, njengesithako esisebenzayo sokhathalelo lwesikhumba, ibonelela ngokhuseleko olubanzi kunye nokulungiswa kolusu, kwaye sesinye sezithako ezihlonitshwa kakhulu kwiimveliso zokhathalelo lwesikhumba.
1. Umthombo kunye neempawu ze-Azelaic Acid
Umthombo:
(1). Ingqolowa kunye nerhasi: I-Azelaic Acid inokutsalwa kwingqolowa nakwirhasi. Ezi nkozo ziqulethe isixa esithile se-Azelaic Acid, enokufunyanwa ngeendlela ezithile zokutsalwa.
(2). I-Humic acid: I-Azelaic Acid ikhona kwi-asidi ye-humic. I-Humic acid yinto yendalo yendalo ehlala ifumaneka kwiindawo zendalo ezifana nomhlaba, i-peat, kunye ne-peat, equlethe isixa esithile se-Azelaic Acid.
(3). Ukuvutshelwa kwefungal: Ukongeza kwimithombo yendalo,98% iAzelaic Acid inokuphinda idityaniswe ngenkqubo yokuvundiswa komngundo. Kwilabhoratri, umngundo unokuguqula ii-substrates ezithile zibe yi-Azelaic Acid, ngaloo ndlela ivelise i-Azelaic Acid ecocekileyo.
(4). I-Chemical synthesis: Ukongeza, i-Azelaic Acid inokuthi ilungiswe ngeendlela ze-chemical synthesis. Ngokusebenzisa iindlela ezithile zokusabela kweekhemikhali, i-Azelaic Acid enesakhiwo esifanayo kunye neepropati zinokudityaniswa.
iimpawu:
(1). Iipropathi ze-Antioxidant: I-Azelaic Acid ineepropathi ze-antioxidant, ezinokunceda ulusu luxhathise uhlaselo lweeradicals zasimahla kwaye lucothise ukuguga kwesikhumba kunye nomonakalo obangelwa kukusabela kwe-oxidative.
(2). I-Anti inflammatory effect: Esi sithako sibonakaliswe ukuba sineempembelelo ezichasayo, ezinokunciphisa ukuvuvukala kwesikhumba, ukunciphisa ubomvu, ukuvuvukala, kunye nokungahambi kakuhle. Ilungele abantu abanolusu olubuthathaka kunye neentlobo zolusu ezithanda ukuba bomvu.
(3). Impembelelo ye-antibacterial: I-Azelaic Acid isetyenziswa ngokubanzi kunyango lwe-acne kunye ne-acne, njengoko inokunciphisa inani lebhaktheriya ebusweni bolusu, ukunciphisa ukuvuvukala, kunye nokunciphisa i-follicle ye-keratinization yeenwele.
(4). Ukulawula i-pigmentation: I-Azelaic Acid inokungenelela kwi-synthesis ye-melanin, inceda ukuthintela ukuveliswa kwe-melanin, ukunciphisa i-pigmentation engaphezulu, kunye nokuphucula ukungalingani kwethoni yesikhumba kunye nemiba ye-pigmentation.
(5). Ukuziqhelanisa ngokubanzi:Iasidi yeAzelaicilungele iintlobo ezahlukeneyo zolusu, kubandakanya ulusu olunamafutha, ulusu olomileyo, kunye nolusu olubuthathaka, kwaye inokunyamezelana.
(6). Ubulali: Xa kuthelekiswa nezinye izithako ezisetyenziselwa ukunyanga amaqhakuva, njenge-benzoic acid kunye ne-benzoyl peroxide, i-Azelaic Acid ayinakucaphuka kunye nobulali obuphezulu.
2. Impembelelo yonyango kwi-acne kunye ne-acne
(1). Impembelelo ye-Antibacterial: I-Azelaic Acid ineempembelelo ze-antibacterial, ngakumbi kwi-Propionibacterium acnes, ebangela i-acne. Ngokunciphisa inani lebhaktheriya ebusweni bolusu, i-Azelaic Acid inokunciphisa ukuvuvukala kunye nokunciphisa ukubunjwa kwe-acne kunye ne-acne.
(2). Ukulawula i-stratum corneum:Ubuninzi beAzelaic Acid inokukhuthaza i-metabolism eqhelekileyo ye-stratum corneum, ukunciphisa i-keratinization kwindawo yokuvula i-follicle yeenwele, kwaye incede ukukhusela ukuvinjelwa kweenwele kunye ne-acne. Kwakhona kunokunciphisa ukuvela kwamabala amnyama kunye namaqhakuva.
(3). Impembelelo echasayo: I-Azelaic Acid inezixhobo ezichasayo, ezinokunciphisa impendulo yokuvuvukala kwesikhumba, ukunciphisa ubomvu, ukuvuvukala, intlungu, kunye nokungahambi kakuhle kwiindawo ze-acne kunye ne-acne.
(4). Ukulawula i-pigmentation: Emva kokuphiliswa kwe-acne kunye ne-acne, kulula ukushiya i-pigmentation, kwaye i-Azelaic Acid inokungenelela kwi-synthesis ye-melanin, inceda ukunciphisa ukubunjwa kwe-pigmentation kunye nokuphucula ithoni yesikhumba esingalinganiyo.
(5). Ukuthintela ukuphindaphinda: Ngenxa yempembelelo ebanzi ye-Azelaic Acid, ayinakunyanga kuphela i-acne ekhoyo kunye ne-acne, kodwa iphinde ithintele ukwenzeka kwe-acne entsha, ukulawula ngokufanelekileyo ukuphindaphinda kwe-acne.
3. Ukulawula umbala kunye nethoni yesikhumba esithambileyo
(1). Ukuvinjelwa kwe-melanin synthesis: I-Azelaic Acid iboniswe ukuba ingenelele kwinkqubo yokwenziwa kwe-melanin. I-Melanin yenye yezinto eziphambili ezikhokelela ekubeni isikhumba sibe nebala. Ngokuthintela ukuhlanganiswa kwe-melanin, i-azelaic acid inokunciphisa ukubekwa kwe-melanin engaphezulu kumphezulu wolusu, ngaloo ndlela iphucula iingxaki ezinje ngebala kunye namabala, kunye nokwenza ithoni yesikhumba ngakumbi.
(2). Ukukhuthaza i-stratum corneum metabolism: I-Azelaic Acid inceda ukukhuthaza imetabolism eqhelekileyo ye-skin stratum corneum. Imetabolism engaqhelekanga ye-stratum corneum inokukhokelela kwithoni yesikhumba esithambileyo, ngelixa iasidi ye-azelaic inokukhawulezisa ukuchithwa kwe-keratin endala kunye nefileyo, ikhuthaze imetabolism, yenza ulusu lube mde kwaye lube buthathaka ngakumbi, kwaye incede ekuphuculeni ingxaki yethoni yesikhumba esithambileyo.
(3). Iimpawu ze-Antioxidant: I-Azelaic Acid ineempembelelo ezithile ze-antioxidant kwaye inokunceda ulusu ukulwa nomonakalo owenziwe ngama-radicals amahhala. I-radicals yamahhala yenye yezinto ezibalulekileyo ezikhokelela ekugugeni kwesikhumba. Ii-Antioxidants zinokunciphisa ii-radicals zamahhala, zinciphise umonakalo wazo eluswini, zincede ukugcina ulusu oluselula kwaye lusempilweni, kwaye lucothise ukubonakala kwethoni yesikhumba esithambileyo.
(4). Ukuvinjwa kwempendulo yokuvuvukala: I-Azelaic Acid nayo ibonakaliswe ukuba ineempembelelo ezichasayo, ezinokunciphisa ukuvutha kolusu. Ukuphendula okuvuthayo akukwazi nje ukubangela ubomvu kunye nokuvuvukala kwesikhumba, kodwa kunokukhokelela kwibala. Ngokuthintela impendulo yokuvuvukala, i-azelaic acid inceda ukunciphisa ukubunjwa kwe-pigmentation kunye nokuphucula ithoni yesikhumba esimnyama.
4. I-Antioxidant kunye ne-anti-inflammatory effects
(1). Impembelelo ye-Antioxidant: Njenge-antioxidant, i-azelaic acid inamandla okunciphisa iiradicals zamahhala. I-radicals yasimahla ziimolekyuli ezingazinzanga ezinokubangela umonakalo oxidative kwiiseli zolusu kunye nezicubu ezidibeneyo, ezikhokelela ekugugeni kwesikhumba, i-pigmentation kunye neminye imiba. I-Azelaic Acid inokusabela kunye ne-radicals yamahhala ukuze inciphise umsebenzi wabo, ngaloo ndlela inciphisa umonakalo weeradicals zamahhala esikhumbeni kunye nokulibazisa inkqubo yokuguga yolusu.
(2). Impembelelo yokuchasana nokuvuvukala: I-Adipic acid yenza i-anti-inflammatory effects ngokuthintela ukuveliswa kunye nokukhululwa kwezinto ezivuthayo. Ukuvuvukala kuyimbangela eqhelekileyo yezifo zesikhumba kunye neempawu, ezifana ne-acne kunye ne-acne. I-Azelaic Acid inokunciphisa ukukrala, ukunciphisa iimpawu ezinjengobomvu bolusu, ukudumba, ukurhawuzelelwa, kunye neentlungu, kunye nokunceda ukuphucula izifo zolusu.
(3). Ukulawula i-epidermal cell metabolism: I-Azelaic Acid inokukhuthaza i-metabolism eqhelekileyo yeeseli ze-epidermal, iphucule ukwakheka kunye nomsebenzi we-stratum corneum, kwaye iphucule isakhono sokuzilungisa ulusu. Oku kunceda ukunciphisa ukwenzeka kunye nokunyanzeliswa kokuvuvukala okungapheliyo, ngaloo ndlela kuncitshiswe umonakalo wokuvuvukala okungapheliyo kwesikhumba.
(4). Iimpendulo ze-alergic zinokuthotywa nge-azelaic acid, enokuthi inciphise ukusabela okugqithisileyo kwesikhumba kwi-allergen kwaye incede ukunciphisa iimpawu zolusu. Ngokunciphisa ukusabela kwe-alergic, i-azelaic acid inokunciphisa ukusasazeka kokuvuvukala kwesikhumba kunye nokunciphisa impembelelo yokuvuvukala eluswini.
Kutheni ukhetha iimveliso zokhathalelo lwesikhumba ezineAzelaic Acid?
(1). Ukwenza mhlophe kunye nokukhanya kwebala:Iipilisi zeAzelaic Acid inokungenelela kwi-melanin synthesis kwaye ikhuthaze i-stratum corneum metabolism, inceda ukunciphisa i-pigmentation kunye ne-freckles, yenza ithoni yesikhumba ngakumbi kwaye ikhanye. Ukukhetha iimveliso zokhathalelo lwesikhumba ezine-Azelaic Acid kunokunceda ukuphucula ithoni yesikhumba esimnyama kunye nemiba yebala.
(2). Iziphumo ezichasene nokudumba kunye ne-sedative: I-Azelaic Acid ineempembelelo ezichasayo, ezinokunciphisa ukudumba kwesikhumba kwaye incede ukunciphisa iingxaki ezinobuthathaka kunye nolusu olune-acne. Ukukhetha iimveliso zokhathalelo lwesikhumba ezineAzelaic Acid kunokunceda ukuthomalalisa ulusu, ukunciphisa ububomvu, ukudumba, kunye nokurhawuzelelwa.
(3). Ukukhuselwa kwe-Antioxidant: I-Azelaic Acid yi-antioxidant esebenzayo enokunciphisa umonakalo kwi-radicals yamahhala kunye nokunciphisa umonakalo wokusingqongileyo eluswini. Ukukhetha iimveliso ze-skincare ezine-Azelaic Acid kunokubonelela ngokhuseleko olongezelelweyo lwe-antioxidant kunye nokulibazisa inkqubo yokuguga yolusu.
(4). Ukuphucula iingxaki ze-acne: I-Azelaic Acid isetyenziswa ngokubanzi ukunyanga iingxaki ze-acne, kwaye iimpawu zayo zokulwa ne-antibacterial kunye ne-anti-inflammatory zinceda ukunciphisa izilonda kunye nokuthintela ukuphindaphinda kwe-acne. Ukukhetha iimveliso zokhathalelo lwesikhumba ezine-Azelaic Acid kunokunceda ukuphucula ulusu oluthanda amaqhakuva kunye nokucoca iipores.
(5). Ukulawula ukukhutshwa kwe-oyile: I-Azelaic Acid ikwadlala indima ekulawuleni ukukhuselwa kwe-oyile, enceda ukulawula ukunyibilika kwe-oyile yolusu okubangelwa kukuphuma kwe-oyile ngokugqithisileyo. Ukukhetha iimveliso ze-skincare ezine-Azelaic Acid kunokulungelelanisa umlinganiselo we-oyile-amanzi eluswini kwaye uphucule imeko yolusu olunamafutha.
Xi'an tgybio Biotech Co., Ltd yiUmvelisi wePowder yeAzelaic Acid , umzi-mveliso wethu unokubonelela nge-OEM/ODM inkonzo yokumisa enye, kubandakanywa ukupakishwa okulungiselelwe kunye neelebhile. Umzi-mveliso wethu unezinye iimveliso ezimhlophe, ezifana ne-hyaluronic acid, i-arbutin, i-kojic acid, njalo njalo. Ukuba unomdla, ungajonga iwebhusayithi yethu. Iwebhusayithi yethu i/ . kwaye ungathumela i-imeyile ku-rebecca@tgybio.com okanye ku-WhatsAPP+86 18802962783.
Ixesha lokuposa: Mar-21-2024
