Fisetin Powder is a natural flavonoid compound iyo inowanikwa zvakanyanya mumichero nemiriwo. Senge ingangoita bioactive molecule, Fisetin yakakwezva kutarisisa kwakapararira munharaunda yesainzi. Chimiro chayo chemakemikari chine akawanda hydroxyl mapoka, izvo zvinoita kuti ive yakanaka antioxidant zvinhu. Tsvagiridzo yakaratidza kuti Fisetin inogona kuita biological chiitiko nekudzora akawanda masaini nzira, inokanganisa maitiro akadai sesero kutenderera uye apoptosis. Nekudaro, kumwe kutsvagisa kunodiwa pane bioavailability uye pharmacokinetics yeFisetin kuratidza maitiro ayo ekuita mumuviri wemunhu. Nekudaro, iyo nyaya yekuti kudyiwa kwemazuva ese kweFisetin kwakachengeteka yakagamuchira kutariswa kwakanyanya. Ichi chinyorwa chichaongorora zvakarongeka kuchengetedzwa kwekutora kwemazuva ese kweFisetin kubva pamaonero akasiyana.
Chii chinonzi Fisetin?
Fisetin inhengo yechisikigo flavonoid, yeboka re flavonoid makomisheni. Inowanikwa mumiti yakawanda, semaapuro, sitirobheri, mandimu, uye inowanikwawo muzvokudya zvakaita sehanyanisi nemagaka. Kutaura nemakemikari, Fisetin iflavonoid ine chimiro chemhete dzebenzene mbiri uye heterocycle imwe, ine akawanda hydroxyl mapoka. Aya ma hydroxyl zvimiro zvinopa Fisetin neakanakisa antioxidant zvimiro.
Fisetin yakakwezva kutarisisa kwakapararira kubva munharaunda yesainzi nekuda kweyakasiyana chimiro chemakemikari uye biological chiitiko. Tsvagiridzo yakaratidza kuti Fisetin inogona kunge iine zvigadziriso pamaitiro ebhayoloji senge cell cycle uye apoptosis, ukuwo iine zvimwe zviitiko zvebiology. In vivo, Fisetin inogona kuita mhedzisiro yayo nekudzora nzira dzakawanda dzekusaina, asi kumwe kutsvagisa pamusoro peiyo bioavailability uye pharmacokinetics inodiwa kuratidza maitiro ayo ekuita mumuviri wemunhu. Pakazara, semusanganiswa wechisikigo, Fisetin ine yakasarudzika kemikari chimiro uye biological chiitiko, uye maitiro ayo ekuita mumuviri wemunhu anokodzera kumwe kutsvagisa.
Fisetin Powder inobatsira
1. The antioxidant effect yeFisetin
98% Fisetinndeye yakasikwa flavonoid komboni ine yakanakisa antioxidant zvimiro.
(1). Iyo kemikari chimiro cheFisetin
Fisetin musanganiswa wechisikigo flavonoid ine molecular formula C ₁æ H ₁₀O ₆. Iyo ine akawanda hydroxyl zvimiro, kusanganisira hydroxyl mapoka pane ayo anonhuwirira mhete.
(2). Neutralization yemahara radicals
Mahara radicals mamorekuru asina kugadzikana anotsvaga maerekitironi kubva kune mamwe mamorekuru kuti agadzikane, zvichitungamira mukukuvadzwa kweiyo oxidative. Iyo hydroxyl chimiro mukati98% Fisetin Podainogona kupa maerekitironi kune emahara radicals, kusaita basa ravo, uye nekudaro kuderedza oxidative kukuvara kwemasero.
(3). Kubviswa kwezvinhu zvinoshanda oxidizing
Sean antioxidant, Fisetin inogona kubvisa inoshanda oxidants senge superoxide anions, hydrogen peroxide, uye hydroxyl radicals. Kuburikidza neiyi clearance effect, Fisetin inogona kuderedza kukuvadzwa kwemaserura kunokonzerwa neoxidative kusagadzikana.
(4). Kudziviswa kwekuita oxidase
Fisetin inogonawo kuvharidzira kushanda kwemamwe ma enzymes e oxidase, akadai se peroxidase uye oxidoreductase, nekudaro kuderedza kufambira mberi kwekuita kwe oxidative mumuviri uye kuderedza chiyero che oxidative stress.
(5). Kurudzira antioxidant enzyme basa
Tsvagiridzo yakaratidza kuti Fisetin inogona kukurudzira zvakakosha antioxidant enzyme zviitiko, senge superoxide dismutase (SOD) uye glutathione peroxidase (GPx), kubatsira masero zvakanyanya kutarisana neoxidative kusagadzikana.
(6). Comprehensive effect
Pakazara, iyo antioxidant mashandiro eFisetin yakawandazvinosanganisira kupa maerekitironi kumisa mahara radicals, kujekesa inoshanda oxidants, inhibiting oxidase chiitiko, uye kusimudzira antioxidant enzyme chiitiko, pakati pedzimwe nzira, kubatanidza kuita antioxidant mhedzisiro uye kudzivirira masero kubva kune oxidative kukuvara.
2. The anti-inflammatory effect yeFisetin
Fisetin inoonekwawo seine akakosha anti-kuzvimba mhedzisiro, ichibatsira kuderedza kuzvimba.
(1). Kugadzirisa kuzvimba masaini nzira
Fisetin inoshandisa anti-inflammatory effects kuburikidza nekukanganisa basa renzira dzakawanda dzekuvhiringidza zviratidzo. Inogona kugadzirisa NF- κ B. MAPK uye STAT nzira dzechiratidzo dzinodzivisa kutaura kwemajini ane chokuita nekuputika, nokudaro kuderedza kuitika uye kupfuurira kwemaitiro ekuputika.
(2). Kudzivisa kusunungurwa kwevamiririri vanopisa
Tsvakurudzo yakaratidza izvozvoPure Fisetin Powderinogona kudzivisa kusunungurwa kwevamiririri vanopisa, zvakadai se tumor necrosis factor- α (TNF)- α）、 Interleukin-1 β (IL-1) β) Uye interleukin-6 (IL-6), nezvimwewo. basa rakakosha mumhinduro yekuzvimba, uye inhibition yeFisetin inobatsira kuderedza kuoma kwekuputika.
(3). Deredza kushandiswa kwemasero anopisa
Fisetin inogona kuderedza kushandiswa uye kupindira kwemasero ekuputika (akadai se macrophages, lymphocytes, uye neutrophils), kuderedza dhigirii iyo masero ekuputika anobudisa vatsigiri vanovhiringidza, uye nokudaro kuderedza kukanganisa kwenyama kunokonzerwa nekuputika.
(4). Kudzivisa kutaura kwemapuroteni ane chokuita nekuputika
Fisetin inogonawo kuvharidzira kutaura kwemamwe mapuroteni ane chekuita nekuzvimba, akadai se inducible nitric oxide synthase (iNOS) uye cyclooxygenase-2 (COX-2), iyo inoita mabasa akakosha mukuita kwekuzvimba. Nekudzivisa kutaura kwavo, Fisetin inobatsira kudzora mhinduro yekuzvimba.
(5). Kusanganiswa kwe antioxidant uye anti-inflammatory effects
Izvo zvakakosha kucherechedza kuti iyo antioxidant mhedzisiro yeFisetin inobatsirawo kune yayo anti-kuzvimba maitiro. Antioxidant zvivakwa zvinogona kuderedza kukuvadzwa kweiyo oxidative kusagadzikana kumaseru, nekudaro ichidzikisa inducible zvinhu zvekuzvimba maitiro uye kuwedzera kuderedza chiyero chekuzvimba.
3. Kudzivirirwa kwenheyo system
(1). Neuron kudzivirira
Tsvakurudzo yakaratidza izvozvoFisetin 98% inogona kusimudzira neuronal kukura uye kukura, uye ine inodzivirira maitiro pane neuroni. Inobatsira kuchengetedza hutano hwehutano hwemaneuroni, inononoka neuronal degeneration, uye ine inodzivirira panheyo system.
(2). Neural conduction regulation
Zvimwe zvidzidzo zvinoratidza kuti Fisetin inogona kubatsira kuvandudza nerve conduction basa, kukurudzira kusunungurwa kwemaurotransmitters uye nerve signal transduction, nokudaro kuvandudza kushanda kwehutano hwehutano.
(3). Kudzora kweiyo neuroprotective majini
Fisetin inogona kukurudzira kuchengetedzwa uye kugadziriswa kwehutano hwemagetsi nekugadzirisa kutaura kwemamwe majini emagetsi, akadai seBDNF (brain derived neurotrophic factor).
Kuchengeteka kwekutora zuva nezuva kweFisetin
(1). Tsvakurudzo yekuongorora mhuka
Kuedza kwemhuka kwakaratidza kuti kunwa zvine mwero kweFisetin kunowanzo kuve kwakachengeteka uye hapana yakakosha mhedzisiro yechepfu yakawanikwa. Zvisinei, zvinofanira kucherechedzwa kuti migumisiro yokuedza mhuka haigoni kutaurwa zvakananga kuvanhu.
(2). Dose uye kusiyana kweumwe neumwe
Maitiro ega ega kuFisetin anogona kusiyana, uye zvinokurudzirwa kutevedzera dhizaini inokurudzirwa nemugadziri paunenge uchidya Fisetin uye kunyatsoongorora maitiro ega ega emuviri.
Kunyange zvazvo Fisetin ine zvakawanda zvingave zvikomborero zvehutano, tsvakurudzo yakawanda yesayenzi inodiwa kutsigira kuchengetedzwa kwekudya kwemazuva ose kweFisetin. Vatengi vanofanira kunyatsofunga nezvekutora kwavo kwezuva nezuva kweFisetin uye kuita sarudzo zvichienderana nemamiriro emunhu. Inokurudzirwa kushandisa Fisetin pasi pekutungamirirwa kwechiremba anobvunzurudza kuti ave nechokwadi chekuchengeteka uye kubudirira.
Xi'an tgybio Biotech Co., Ltd inogadzira fisetin poda, tinogona kupaFisetin capsuleskanafisetin zvinowedzera , isu tine timu yehunyanzvi yekukubatsira iwe kugadzira kurongedza uye mavara, kusanganisira akagadzirirwa kurongedza uye mavara. Webhusaiti yedu ndeye /. Kana uchifarira, unogona kutumira e-mail ku rebecca@tgybio.com kana WhatsAPP +86 18802932783.
Nguva yekutumira: Mar-19-2024
