Ingabe i-PQQ Ingcono kune-CoQ10?
Isingeniso:
Emkhakheni wezithako zokudla, ama-antioxidants adlala indima ebalulekile ekuthuthukiseni impilo nobungqabavu buphelele. Abadlali ababili abamqoka kule nkundla ngabaI-PQQ (Pyrroloquinoline quinone)futhiI-CoQ10 (Coenzyme Q10) . Bobabili baziwa ngamandla abo okusekela impilo yamaselula kanye nokulwa nokucindezeleka okwenziwe nge-oxidative. Kodwa yimuphi obusa ngokuphakeme? Ake sijule kulo mbuzo futhi sembule imfihlakalo yama-antioxidants.
Ukuqonda Antioxidants:
Ngaphambi kokuthi siqhathanise i-PQQ ne-CoQ10, kubalulekile ukuqonda ukubaluleka kwama-antioxidants. Lezi zinhlanganisela zinciphisa ama-radicals mahhala, okungama-molecule ayingozi angalimaza amangqamuzana futhi abe nomthelela ekugugeni nasezifweni. Ngokukhipha ama-radicals mahhala, ama-antioxidants asiza ukuvikela amangqamuzana ekucindezelekeni kwe-oxidative futhi agcine inhlalakahle yonke.
I-PQQ: Omusha Onamandla:
I-PQQ Powder ithole ukunakwa eminyakeni yamuva nje ngezakhiwo zayo ezihlukile. Isebenza njenge-cofactor ye-redox futhi ibamba iqhaza ezindleleni zokubonisa amaselula, ekugcineni ikhuthaze i-mitochondrial biogenesis. Lokhu kusho ukuthi i-PQQ ingase ithuthukise ukukhiqizwa kwamandla eselula futhi isekele umsebenzi we-mitochondrial usuwonke, obalulekile empilweni engcono namandla.
1. I-antioxidant mechanism yeI-Pyrroloquinoline Quinone Powder Pqq powder:
I-PQQ (i-Pyroquinoline Quinone) iyi-antioxidant enamandla, futhi izindlela zayo eziyinhloko zokulwa ne-antioxidant zihlanganisa:
- Ukunciphisa ama-radicals mahhala:I-PQQ ingasabela ngama-radicals wamahhala ukuze izinze la mamolekyuli asebenza kakhulu futhi inciphise ukulimala kwawo kumaseli.
- Ukwandisa umsebenzi we-enzyme ye-antioxidant:Ucwaningo luye lwabonisa lokhoI-Pyrroloquinoline Quinone Disodium Usawotiingakhuthaza umsebenzi we-antioxidant enzymes, njenge-superoxide dismutase (SOD) kanye ne-glutathione peroxidase (GPx), iqhubeke nokuthuthukisa amandla e-antioxidant amaseli.
- Ukuvikela i-mitochondria: I-Mitochondria iyindawo eyinhloko yokukhiqiza amandla ngaphakathi kwamaseli kanye nenhloso enkulu yokucindezeleka okwenziwe nge-oxidative. I-PQQ ngokungaqondile isebenzisa imiphumela ye-antioxidant ngokuvikela i-mitochondria emonakalweni we-oxidative, ikhuthaze umsebenzi wayo ojwayelekile.
2.Ukuqhathanisa phakathi kwe-PQQ namanye ama-antioxidants:
- Uma kuqhathaniswa ne-CoQ10 : I-PQQ, i-PQQ inokutholakala okuphezulu kwe-bioavailability ngakho-ke ingase isebenze ngokugqama kakhulu ngokwezakhiwo ze-antioxidant. Ngaphezu kwalokho, i-PQQ ingakhuthaza ukukhiqizwa kwe-mitochondrial futhi inikeze imithombo yamandla eyengeziwe kumaseli.
- Ukuqhathanisa ne-Vitamin C kanye ne-Vitamin E : Nakuba i-PQQ ne-Vitamin C kanye ne-Vitamin E kokubili kuyi-antioxidant enamandla, izindlela zabo zokwenza kanye nemiphumela kuhluke kancane. I-PQQ ibandakanyeka kakhulu ekulawuleni ukusayinda kwamaselula kanye nokusebenza kwe-mitochondrial, futhi uma kuqhathaniswa namavithamini C no-E, i-PQQ ingaba nomthelela ophelele wokulwa ne-antioxidant.
I-CoQ10: Umpetha Osunguliwe:
Ngakolunye uhlangothi, iCoenzyme Q10 sekuyisikhathi eside idunyiswa njenge-antioxidant enamandla. Idlala indima ebalulekile ochungechungeni lwezokuthutha lwama-electron, lula ukukhiqizwa kwe-ATP futhi inikeze amandla amaselula. Ukwengeza, i-CoQ10 isebenza njenge-antioxidant enamandla, ivikela amangqamuzana emonakalweni we-oxidative futhi isekele impilo yenhliziyo.
- I-Neutralizing radicals yamahhala: Omunye wemisebenzi eyinhloko ye-coenzyme Q10 powder emangqamuzaneni ukuqeda ama-radicals mahhala futhi unciphise umonakalo wokucindezeleka okwenziwe nge-oxidative kumaseli. Ama-radicals amahhala angama-molecule asebenza kakhulu ane-electron eyodwa engabhanqiwe esabelana nama-macromolecules ebhayoloji kumaseli, njengamaprotheni, ama-lipids, ne-DNA, okuholela ekulimaleni kwamangqamuzana nokuguga. I-Coenzyme Q10 inciphisa ama-radicals mahhala ngokunikela ngama-electron, inciphisa ukulimala kwawo kumaseli.
- Ukuvuselela ezinye izinto ezilwa ne-antioxidant: I-Coenzyme Q10 ingaphinda ikhiqize ezinye izinto ezilwa ne-antioxidant, njenge-vitamin E, iphinde isebenze futhi ithuthukise umphumela wayo wokulwa ne-antioxidant.
- Ukuvikela umsebenzi we-mitochondrial: I-Mitochondria yizikhungo zokukhiqiza amandla ngaphakathi kwamaseli futhi enye yezinhloso eziyinhloko zokucindezeleka okwenziwe nge-oxidative. I-Coenzyme Q10 ibamba iqhaza enqubweni yokudlulisa i-electron yeketango lokuphefumula le-mitochondrial, isiza ukukhiqiza amandla adingwa amaseli nokuvikela i-mitochondria emonakalweni we-oxidative, igcine ukusebenza kwayo okuvamile.
- Ukunciphisa ukucindezeleka okwenziwe nge-oxidative: Umphumela we-antioxidant we-coenzyme Q10 unganciphisa amazinga okucindezeleka okwenziwe nge-oxidative, ugcine ibhalansi ye-redox yeselula, usize ukuvimbela ukulimala kwamangqamuzana nokuguga okubangelwa ukucindezeleka okwenziwe nge-oxidative, futhi ngaleyo ndlela kuvikele impilo.
Ukuhlaziya okuqhathanisayo:
Uma uqhathanisa i-PQQ ne-CoQ10, kunezici ezimbalwa ezisebenzayo:
- I-Bioavailability: I-CoQ10 yaziwa kakhulu ngokungabi bikho kwayo kahle uma kuqhathaniswa, okusho ukuthi ingxenye ebalulekile ingase ingamuncwa umzimba ngempumelelo. Ngokuphambene, i-PQQ ikhombisa ukubakhona okuphezulu kwe-bioavailability, okungase kuholele ezinzuzweni zezempilo ezishiwo kakhudlwana.
- Ukusekela kwe-Mitochondrial: KokubiliI-Pqq Pyrroloquinoline Quinone Powder kanye ne-CoQ10 idlala indima ebalulekile ekusekeleni umsebenzi we-mitochondrial. Kodwa-ke, ikhono le-PQQ lokukhuthaza i-mitochondrial biogenesis liyayihlukanisa, iphakamisa izinzuzo ezibanzi zokukhiqiza amandla eselula kanye nobungqabavu buphelele.
- I-Synergistic Effects: Ezinye izifundo ziphakamisa ukuthi i-PQQ ne-CoQ10 ingase ibe nemiphumela yokuhlangana lapho ihlanganiswa. Ngokuqondisa izici ezihlukene zempilo yeselula, lawa ma-antioxidants angase aphelelisane futhi anikeze izinzuzo ezithuthukisiwe.
Isiphetho:
Empikiswaneni phakathi kwe-PQQ ne-CoQ10, akekho owinile ocacile. I-antioxidant ngayinye inikeza izinzuzo eziyingqayizivele futhi ingase ifanele abantu abahlukene ngokusekelwe ezinhlosweni zabo zezempilo nezidingo. Nakuba i-CoQ10 inedumela lesikhathi eside njenge-antioxidant enamandla, i-PQQ ivela njengentsha ethembisayo enezinzuzo ezingaba khona mayelana ne-bioavailability kanye nokusekelwa kwe-mitochondrial.
Ekugcineni, ukukhetha phakathi kwe-PQQ ne-CoQ10 kungase kuncike kulokho okuthandwayo nokucatshangelwa kwezempilo. Kulabo abafuna ukwesekwa okuphelele kwe-antioxidant, ukuhlanganisa zombili izithasiselo kungaba isu elihlakaniphile lokusebenzisa imiphumela ye-synergistic kanye nokukhulisa impilo yamaselula.
I-Xi'an tgybio Biotech Co., LTDI-PQQ Powder kanye ne-Coenzyme Q10 Powder umphakeli, singanikezaAmaphilisi e-PQQ / PQQ IzithasiselofuthiI-Coenzyme Q10 Capsules / Coenzyme q10 Supplements . Imboni yethu isekela isevisi ye-OEM/ODM One-stop, okuhlanganisa ukupakishwa okungokwezifiso namalebula. Uma unentshisekelo, ungathumela i-imeyili kurebecca@tgybio.comnoma WhatsApp +8618802962783.
Izithenjwa:
- Harris, CB, Chowanadisai, W., Mishchuk, DO, & Satre, MA (2013). I-Pyrroloquinoline quinone (PQQ) yehlisa i-lipid peroxidation futhi ithuthukisa ukusebenza kwe-mitochondrial ebuchosheni begundane kanye ne-mitochondria yesibindi. I-Mitochondrion, 13(6), 336-342.
- Littarru, GP, & Tiano, L. (2007). Izakhiwo ze-Bioenergetic kanye ne-antioxidant ye-coenzyme Q10: intuthuko yakamuva. I-Molecular Biotechnology, 37(1), 31-37.
- Nakano, M., Ubukata, K., Yamamoto, T., & Yamaguchi, H. (2009). Umthelela we-pyrroloquinoline quinone (PQQ) esimweni sengqondo sabantu abaneminyaka ephakathi kanye nasebekhulile. Isitayela SOKUDLA, 21(13), 50-53.