Yintoni i-Artesunate Powder?

I-Artesunate sisitshabalalisi esikhawulezayo esichasene nePlasmodium falciparum kwisigaba se-erythrocytic, esisebenza ngokuchaseneyo. Inokulawula ngokukhawuleza uhlaselo oluqatha lwemalariya emva kokuyithatha. Isetyenziselwa ukuhlangula i-malaria eyingozi efana nohlobo lobuchopho kunye nohlobo lwe-icteric, kunye nokunyangwa kwe-falciparum malaria.

Indlela ye-artesunate yi-artemisinin. Iqala isebenze kwi-membrane ye-vesicle yokutya, inwebu yomphezulu kunye ne-mitochondria yePlasmodium. Eyesibini yinwebu yenyukliya kunye ne-endoplasmic reticulum. Ukongeza, nayo inempembelelo ethile kwi-chromatin kwi-nucleus. Ngenxa yokuba le mveliso iqala ukusebenza kwi-membrane ye-bubble yokutya, ngaloo ndlela ivalela ukungena kwezondlo, ibangela i-malariya parasite ukuba ilambe ngokukhawuleza i-amino acids, yenza ngokukhawuleza amaqamza e-autophagic, kwaye iqhubeke nokukhutshwa emzimbeni, ilahlekelwe sisixa esikhulu se-cytoplasm kwaye sife. .

Umsebenzi we-Artesunate:

I-Artesunate yi-arhente ye-antimalarial. Yimveliso ye-hemisuccinate enyibilikayo emanzini ye-dihydroartemisinin.

I-Artemisinin yi-sesquiterpene lactone ebekwe yodwa kwi-Artemisia annua, imifuno ebikade isetyenziswa e-China ukunyanga isifo seengcongconi.

I-Artesunate kunye ne-metabolite yayo esebenzayo i-dihydroartemisinin zi-schizonticides zegazi ezinamandla, ezisebenzayo ngokuchasene nenqanaba le-ring ye-parasite.

I-Artesunate ilungele ukunyanga isifo seengcongconi, kuquka isifo seengcongconi. Ikwasebenza ngokuchasene neendidi ze-mefloquine ezixhathisayo ze-P. falciparum. Ayizinzile kwisisombululo esingathathi hlangothi kwaye ke ifumaneka kuphela kwiinaliti njenge-artesunic acid.

Isicelo

1. Isetyenziswe kwindawo yokutya, iye yaba yinto entsha ekrwada esetyenziswa kushishino lokutya nesiselo;
2. Isetyenziswe kwintsimi yemveliso yezempilo, yimveliso yendalo yempilo yokulawula ukulala;
3. Ukusetyenziswa kwintsimi yamachiza, kunye nefuthe elihle lokunyanga i-hepatitis.

Ugcino oluCetyisiweyo:
I-Artemisinin iyacetyiswa ukuba igcinwe kwindawo epholileyo, eyomileyo, ivalwe ngaphandle emoyeni. Sithumela imveliso kwisikhwama esitywinwe kabini esinokuphinda sivalwe. Esinye isikhongozeli siyacetyiswa ukuba sitywinwe emoyeni wangaphandle.