Melemo ea ho nka L-Carnitine ke efe?

L-Carnitine phofo , e le tlatsetso e tloaelehileng ea phepo e nepahetseng, e fumane tlhokomelo e ngata litabeng tsa bophelo bo botle le boikoetliso. E nkoa e na le melemo e mengata e ka 'nang ea e-ba teng, ho tloha ho fana ka matla, ho khothalletsa ho theola boima ba' mele, ho tšehetsa bophelo bo botle ka kakaretso. Sengoliloeng sena se tla hlahloba ka botlalo melemo ea L-Carnitine ho u thusa ho utloisisa karolo ea eona le ho u fa motheo oa ho etsa liqeto ho latela lipatlisiso tsa mahlale.

Tlhaloso ea 1.L-Carnitine

1.1 Tlhaloso le mokhoa oa ts'ebetso ea L-Carnitine

L-Carnitine ke amino acid e seng ea bohlokoa e entsoeng ka har'a sebete le liphio, hape e ka fumanoa lijong. Mosebetsi oa eona o ka sehloohong ke ho thusa mafura a acids ho kena mitochondria ka lera la mitochondrial bakeng sa ho senyeha ha oxidative, ka hona ho hlahisa matla le ho khothalletsa metabolism e tloaelehileng ea lisele tsa 'mele.

Haholo-holo, mokhoa oa ts'ebetso oa L-Carnitine o kenyelletsa lintlha tse latelang:

1. Lipalangoang tsa mafura a mafura: L-Carnitine e ka tlama ka mafura a mafura ho theha L-Carnitine fatty acid complexes, e ntan'o thusa mafura a mafura ho feta ka har'a lera le ka ntle la mitochondria ka Carnitine transferases le ho kena ka hare ho mitochondria β Oxidative degradation e hlahisa ATP. matla. Mokhoa ona o bitsoa fatty acid transport.
2. Ho khothaletsa tlhahiso ea matla: Phello ea L-Carnitine e ka eketsa ts'ebetso ea li-enzyme ho mitochondria, ea potlakisa ho senyeha ha oxidative ea mafura a mafura le tlhahiso ea matla a ATP, ka hona ho matlafatsa matla a 'mele.
3. Ho fokotsa ho bokella lactate: Tšebeliso ea L-Carnitine e ka fokotsa ho bokella lactate, e leng molemo bakeng sa ho lelefatsa nako le matla a boikoetliso ba mamello.
4. Tšehetso bakeng sa bophelo bo botle ba pelo: L-Carnitine e ka ntlafatsa tšebeliso ea mafura a acid ka myocardium, ea khothalletsa metabolism ea matla le ho sebetsa ha mesifa ea pelo, kahoo e thibela ho hlaha ha mafu a pelo.

1.2 Mohloli le foromo ea tlatsetso

Phofo e hloekileng ea L-Carnitine e ka fumanoa lijong tse sa tšoaneng, ho akarelletsa nama, tlhapi, lihlahisoa tsa lebese le linaoa. Lijo tse thehiloeng ho liphoofolo tse kang nama e khubelu, sebete sa nama ea khomo le nama ea kolobe li na le litaba tse ngata, athe lijo tse entsoeng ka limela tse kang soya, chisi, makotomane le lialmonde li na le lintho tse fokolang.

Ntle le ho ja lijo, L-Carnitine e ka boela ea tlatsetsoa ka li-supplement tsa molomo. Mefuta e tloaelehileng ea supplementation e kenyelletsa:

1. L-Carnitine hydrochloride: Ena ke mokhoa o tloaelehileng ka ho fetisisa oa tlatsetso, hangata o hlahang ka phofo kapa foromo ea capsule, e bonolo ho e metsa le ho cheka.
2. Acetyl-L-Carnitine: Foromo ena e na le monyetla oa ho tšela mokoallo oa mali-boko, ho tšehetsa bophelo bo botle ba boko le ts'ebetso ea kelello.
3. L-Carnitine L-Tartrate: Foromo ena e loketse haholoanyane bakeng sa ho ntlafatsa ts'ebetso ea liatleletiki le ho khothalletsa ho hlaphoheloa ha mesifa.

2.Fana ka matla le ho ntlafatsa ts'ebetso ea liatleletiki

2.1 Fatty acid metabolism le tlhahiso ea matla

1. Ho khothaletsa lipalangoang tsa acid e mafura: L-Carnitine e tlama le li-acid tse mafura ho etsa li-complexes, ho thusa mafura a acids ho phunyeletsa lera la mitochondrial le ho kena ho mitochondria bakeng sa ho senyeha ha oxidative, ho hlahisa matla.
2. Ho ntlafatsa tlhahiso ea matla: L-Carnitine e eketsa ts'ebetso ea li-enzyme ho mitochondria, e potlakisa ho senyeha ha oxidative ea mafura a acid le tlhahiso ea matla a ATP, kahoo e matlafatsa matla a 'mele.
3. Ho fokotsa ho bokella lactate: Tšebeliso ea L-Carnitine e ka fokotsa ho bokella lactate, e leng molemo bakeng sa ho lelefatsa nako le matla a boikoetliso ba mamello.
4. Tšehetso bakeng sa bophelo bo botle ba pelo: L-Carnitine e ntlafatsa tšebeliso ea mafura a acid ka myocardium, e khothalletsa metabolism ea matla le ho sebetsa ha mesifa ea pelo, 'me e thibela ho hlaha ha mafu a pelo.

2.2L-Carnitine phofo e ngatae na le phello ea ho lieha ho khathala le ho ntlafatsa mamello.

2.3 L-Carnitine e thusa ho khothalletsa ho hlaphoheloa ha mesifa le ho lokisa, ho fokotsa mokhathala oa mesifa, ho ntlafatsa ts'ebetso ea boikoetliso, le ho matlafatsa mesifa ea mesifa.

3.Ho khothalletsa ho lahleheloa ke boima ba 'mele le mafura a oxidation

3.1 Ts'ebetso ea ho tsamaisa asiti ea mafura le lits'ebetso tsa oxidation

L-Carnitine ke amino acid e seng ea bohlokoa e bapalang karolo ea bohlokoa ho metabolism ea mafura. Mafura a mafura ke o mong oa mehloli e meholo ea matla 'meleng, empa ha a khone ho kena ka ho toba mitochondria bakeng sa metabolism ea oxidative. L-carnitine e khothalletsa ho tsamaisa le ho oxidation ea mafura acid, e thusa ho li tsamaisa ho tloha cytoplasm ho ea ka hare ho mitochondria, kahoo e kenya letsoho ho metabolism ea mafura a mafura.

Li-acids tse mafura li kopana le L-carnitine ka cytoplasm ho etsa mafura acylcarnitine, a kenang mitochondria ka mojari oa mafura a acylcarnitine transporter (CPT). Ka har'a mitochondria, acylcarnitine e mafura butle-butle e tšeloa oxid ebe e robeha ka ketso ea mafura a acid oxidase, e hlahisang matla a tšebeliso ea lisele.

L phofo ea carnitine e sebetsa joalo ka sejari ts'ebetsong ena, e khothaletsa ho tsamaisa le ho tsamaisa oxidative metabolism ea mafura acid, ka hona e thusa ho boloka phepelo ea matla le ho leka-lekana ha lipid metabolism liseleng. Ka hona, L-carnitine e sebelisoa haholo litabeng tsa phepo ea boikoetliso le bophelo bo botle e le tlatsetso ea phepo e nepahetseng ho thusa ho laola metabolism ea mafura le ho ntlafatsa ts'ebetso ea boikoetliso.

3.2 Fokotsa ho bokellana ha mafura le ho eketsa ho chesa mafura

1. Ntlha ea pele, L-carnitine e ka khothalletsa lipalangoang le metabolism ea oxidative ea mafura a acids, a li tsamaisa ho tloha cytoplasm ho ea ka hare ho mitochondria, ho khothalletsa ho senyeha ha oxidative ea mafura le ho fokotsa ho bokella ha bona.
2. Ea bobeli, L-carnitine e ka boela ea eketsa tekanyo ea oxidation ea mafura a acids ka mitochondria, ea ntlafatsa matla a ho tuka ha mafura, 'me ea etsa hore mafura a sebelisoe haholo e le mohloli oa matla, kahoo a fokotsa ho bokella mafura.
3. Ho phaella moo, L-carnitine e ka boela ea khothalletsa ho hōla ha mesifa le metabolism, ho eketsa tšebeliso ea mesifa ea mafura, le ho tsoela pele ho khothalletsa ho chesa mafura.

4.Ho khothalletsa ts'ebetso ea boko le ho thibela botsofali

Ntlha ea pele, L-carnitine e phetha karolo ea ho laola metabolism ea neurotransmitter le neuroprotection bokong. E thusa ho boloka ts'ebetso e tloaelehileng ea li-neurone, e khothalletsa ho qaptjoa le ho lokolloa ha li-neurotransmitters, 'me kahoo e thusa ho boloka tsamaiso ea methapo e tloaelehileng le mosebetsi oa boko.

Taba ea bobeli, L-carnitine e boetse e na le litlamorao tsa antioxidant, e thusa ho felisa li-radicals tsa mahala le ho fokotsa tšenyo ea khatello ea oxidative bokong, ka hona e thusa ho sireletsa lisele tsa boko ho tsoa tšenyo ea oxidative.

Ho phaella moo, L-carnitine e ka khothalletsa ho potoloha ha mali bokong, ho eketsa phepelo ea mali le phepo e nepahetseng bokong, le ho thusa ho ntlafatsa metabolism le mosebetsi oa boko.

Xi'an tgybio Biotech Co., Ltd keL-carnitine fektheri, fektheri ea rona e ka fana kaLi-capsules tsa L-carnitineleLi-supplement tsa L-carnitine . Feme ea rona e ka fana ka ts'ebeletso ea OEM/ODM One-Stop, ho kenyelletsa le liphutheloana le lileibole tse ikhethileng. Haeba u batla ho tseba haholoanyane, u ka romella lengolo-tsoibila hoRebecca@tgybio.comkapa WhatsApp+8618802962783.

Iteanye le rona

Qetello:

L-Carnitine, e le tlatsetso ea phepo e nepahetseng, e na le melemo e fapaneng e ka bang teng, ho kenyelletsa ho matlafatsa matla, ho khothaletsa tahlehelo ea boima ba 'mele, ho ts'ehetsa bophelo bo botle ba pelo, ho khothaletsa ts'ebetso ea boko, le ho ts'ehetsa bophelo bo botle ba metabolism. Leha ho le joalo, ho motho ka mong, phello ea sebele e ka fapana ho itšetlehile ka liphapang tsa motho ka mong. Pele u nahana ho sebelisa L-Carnitine, ka kopo ikopanye le ngaka kapa setsebi sa tlhokomelo ea bophelo bo botle bakeng sa keletso.

Referense:

1. Brass EP. Carnitine e eketsehileng le boikoetliso. Ke J Clin Nutr. 2000 Aug;72(2 Suppl):618S-23S. doi: 10.1093/ajcn/72.2.618S. PMID: 10919961.
2. Fielding R, Riede L, Lugo JP, Bellamine A. l-Carnitine Supplementation ka Pholiso ka mor'a ho ikoetlisa. Limatlafatsi. 2018 Mar 13;10(3):349. doi: 10.3390/nu10030349. PMID: 29534496; PMCID: PMC5872767.
3. Pooyandjoo M, Nouhi M, Shab-Bidar S, Djafarian K, Olyaeemanesh A. Phello ea (L-) carnitine ho lahleheloa ke boima ba 'mele ho batho ba baholo: tlhahlobo e hlophisitsoeng le tlhahlobo ea meta ea liteko tse laoloang ka nako e sa lekanyetsoang. Obes Rev. 2016 Oct;17(10):970-6. doi: 10.1111/obr.12436. Epub 2016 Jun 22. PMID: 27335245.
4. Malaguarnera M. Carnitine derivatives: molemo oa bongaka. Curr Opin Gastroenterol. 2012 Mar;28(2):166-76. doi: 10.1097/MOG.0b013e328350a4b0. PMID: 22234221.
5. Hoppel C, Theuretzbacher AK. L-carnitine ka thibelo ea bobeli ea lefu la pelo: tlhahlobo e hlophisitsoeng le tlhahlobo ea meta. Mayo Clin Proc. 2013 Nov;88(11):544-51. doi: 10.1016/j.mayocp.2013.03.020. Epub 2013 Sep 26. PMID: 24075555; PMCID: PMC4191597.