Tuuina atu Mea'ai Vasega Mea'ai Supplements Alpha-Ketoglutaric acid/2-Ketoglutaric acid

1.alpha ketoglutaric acid fa'aaogaina e pei o le tricarboxylic acid cycle

α- Ketoglutarate o se mea taua tele i le microbial tricarboxylic acid cycle, lea o se node autu e fesoʻotaʻi ai le metabolism carbon nitrogen i sela. E maua pe a uma le isocitric acid ma luma ole succinyl coenzyme A ile taamilosaga. I lenei vaega, e mafai ona faʻatupuina le tali anaplerotic e ala i le Transamination of glutamic acid α- O le faʻamoemoe o le faʻaopoopoina o lenei metabolite vavalalata ma le ketoglutaric acid e mafai foi ona ausia e ala i le gaioiga o le glutamate dehydrogenase i luga o le glutamate.

2. alafa-ketoglutaric acid faʻaaogaina mo le faʻatupuina o amino acids

Glutamic acid e mafai ona gaosia le glutamine i lalo o le gaioiga o le glutamine synthase, lea e faʻaaogaina ai se mole o le ATP e gaosia ai le glutamine phosphate; O lenei oloa vavalalata e osofaʻia e le ammonia e avea o se nucleophilic reagent, e mafua ai le faʻavaeina o le glutamine ma le phosphate inorganic.
3. alpha ketoglutaric acid faʻaaogaina mo meaʻai faaopoopo
α- Ketoglutaric acid o lo'o fa'atau atu e fai ma mea'ai fa'aopoopo i lalo o le igoa tau fefa'ataua'iga AKG po'o le a-KG ma fa'atau atu i tagata fa'amalosi tino po'o tagata fau tino. Fai mai le tagata faʻatau e mafai e lenei mea ona faʻaleleia le faʻatinoga i le pito i luga o aʻoaʻoga. Fai mai le tagata faʻatau o lenei mea e faʻavae i luga o "suʻesuʻega e faʻaalia ai o le tele o ammonia e mafai ona fusifusia i le α- Ketoglutaric acid ua aveesea e faʻaitiitia ai le tele o faʻafitauli e mafua mai i le ammonia poisoning. oona e na'o tagata mama'i na faia le hemodialysis.