Waikawa Alpha-Ketoglutariche koiora nui, tetahi o nga hua takawaenga nui i roto i te huringa waikawa tricarboxylic, he kaikawe hauota me te matū tohu i roto i te waikura ngota.
α-Ketoglutaric acid he rāpoi ngota koiora nui, ko tetahi o nga hua takawaenga nui i roto i te huringa waikawa tricarboxylic, a he kaikawe hauota me te matū tohu i roto i te waikura ngota. He whai waahi nui ki roto i te paopaotanga o nga pūtau microbial, he mea nui ano hoki mo te whakahiatotanga o nga waikawa amino pukapuka matū maha me nga pūmua.
2-Ketoglutaric waikawaka whai wāhi ki te huringa waikawa tricarboxylic i roto i te vivo ki te whakaputa waikawa amino, ka taea te whakamahi hei taapiri kai.
ingoa hua | Waikawa Alpha-Ketoglutaric |
CAS | 328-50-7 |
Te ahua | Te paura ma |
Tātai rāpoi | C5H6O5 |
Iwi Whakarewa | 113-115 °C |
Taupānga | Te taapiri kai |
α- Ketoglutaric acid ka taea te whakamahi hei whakarei kai hei waahanga o nga inu kai kai hakinakina; Ka taea hoki te whakamahi hei takawaenga waro, reagents biochemical, reagents taurite mo te whakamatautau mahi ate, me nga taapiri whakarei tinana.
1.te waikawa alpha ketoglutaric i whakamahia hei huringa waikawa tricarboxylic
Ko te α- Ko te Ketoglutarate he takawaenga metabolic nui i roto i te huringa waikawa tricarboxylic microbial, he node matua e hono ana i te hauota hauota i roto i nga pūtau. Kei muri i te waikawa isocitric me te aroaro o te succinyl coenzyme A i roto i te huringa. I tenei wahanga, ka taea te whakaputa i te tauhohenga anaplerotic na roto i te Whakawhitinga o te waikawa glutamic α- Ko te kaupapa o te taapiri i tenei metabolite takawaenga me te waikawa ketoglutaric ka taea hoki ma te mahi a te glutamate dehydrogenase i runga i te glutamate.
2. alpha-waikawa ketoglutaric whakamahia mo te Hanga waikawa amino
Ka taea e te waikawa Glutamic te whakaputa glutamine i raro i te mahi a te glutamine synthase, e whakamahi ana i te ngota ngota o te ATP hei whakaputa i te glutamine phosphate; Ko tenei hua takawaenga ka whakaekehia e te haukini hei reagent nucleophilic, ka puta te hanganga o te glutamine me te phosphate pararopi.
3. te waikawa alpha ketoglutaric e whakamahia ana mo nga taapiri kai
α- Ketoglutaric acid ka hokona hei taapiri kai i raro i te ingoa hokohoko AKG, a-KG ranei, ka hokona ki te hunga kaingākau tinana, ki te hanga tinana ranei. E kii ana te kaihoko ka taea e tenei matū te whakapai ake i te mahi i te taumata o te whakangungu. E kii ana te kaihoko ko tenei i runga i "te rangahau e tohu ana ka taea e te haukini nui te here ki te α- Ka tangohia te waikawa Ketoglutaric ki te whakaiti i nga raruraru maha na te paihana o te haukini. Ko te paihana mo nga turoro kua mate hemodialysis anake.
Tūemi | Whakatakotoranga | Hua |
Te ahuatanga | tioata ma, tata ma ranei paura tioata | karaihe ma |
Te rewa | 113~117 ℃ | 114~116℃ |
Fe | ≤10ppm | Ka rite |
Whakawhitinga | ≥97% | 98.4% |
Ngaronga i te whakamaroke | ≤0.5% | 0.12% |
Te toenga i runga i te mura | ≤0.2% | 0.02% |
Te whakarewa taumaha | ≤10ppm | Ka rite |
Te whakamatautau | ≥99% | 99.48% |
Whakamutunga | Ka rite nga hua ki nga paerewa umanga |
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