Na-eweta Mmeju Nri Nri Nri Alfa-Ketoglutaric/2-Ketoglutaric acid
Alfa-Ketoglutaric acidbụ ihe dị mkpa biomolecule, otu n'ime ihe dị mkpa n'etiti ngwaahịa na tricarboxylic acid okirikiri, onye na-ebu nitrogen na ihe symbiotic ihe na molekul oxidation.
α-Ketoglutaric acid bụ ihe dị mkpa dị ndụ molekul, otu n'ime ihe dị mkpa etiti ngwaahịa na tricarboxylic acid okirikiri, na bụ nitrogen transporter na ihe symbiotic ihe na molekul oxidation. Ọ na-arụ ọrụ dị mkpa na metabolism nke mkpụrụ ndụ microbial ma bụrụkwa ihe dị mkpa maka njikọ nke ọtụtụ akwụkwọ kemịkal amino acid na protein.
2-Ketoglutaric acidna-esonye na okirikiri tricarboxylic acid na vivo iji mepụta amino acids, enwere ike iji ya mee ihe mgbakwunye nri.
na ịdị ọcha dị elu 99% maka ire ere, ọ na-ere ezigbo ọkụ ugbu a, anyị na-enye ọnụahịa dị ala na ịdị elu dị elu, ị nwere ike.kpọtụrụ anyịmaka nlele efu na nkọwa ngwaahịa ndị ọzọ.
| Aha ngwaahịa | Alfa-Ketoglutaric acid |
| CAS | 328-50-7 |
| Ọdịdị | Ọcha ntụ ntụ |
| Usoro ihe omimi | C5H6O5 |
| Ebe mgbaze | 113-115 Celsius C |
| Ngwa | Ihe mgbakwunye nri |
α- Ketoglutaric acid enwere ike iji ya dị ka ihe na-edozi ahụ dị ka akụkụ nke ihe ọṅụṅụ na-edozi egwuregwu; Enwere ike iji ya dị ka etiti etiti, biochemical reagents, reagents dakọtara maka nyocha ọrụ imeju, yana mgbakwunye nkwalite anụ ahụ.
1.A na-eji alfa ketoglutaric acid dị ka okirikiri tricarboxylic acid
α- Ketoglutarate bụ ihe dị mkpa metabolic etiti na microbial tricarboxylic acid okirikiri, nke bụ isi ọnụ na-ejikọta carbon nitrogen metabolism na cell. Ọ dị mgbe isocitric acid na tupu succinyl coenzyme A na okirikiri. N'akụkụ a, enwere ike ịmepụta mmeghachi omume anaplerotic site na Transamination nke glutamic acid α- Ebumnuche nke ịgbakwunye metabolite nke etiti a na ketoglutaric acid nwekwara ike nweta site n'omume glutamate dehydrogenase na glutamate.
2. alfa-A na-eji ketoglutaric acid mepụta amino acid
Glutamic acid nwere ike ịmepụta glutamine n'okpuru ọrụ nke glutamine synthase, nke na-eji molecule nke ATP mepụta glutamine phosphate; Amonia na-awakpo ngwaahịa etiti a dị ka nucleophilic reagent, na-ebute nhazi nke glutamine na phosphate inorganic.
3. alfa ketoglutaric acid eji emeju nri nri
α- Ketoglutaric acid A na-ere ya dị ka ihe mgbakwunye nri n'okpuru aha ahia AKG ma ọ bụ a-KG ma na-ere ya ndị na-anụ ọkụ n'obi ma ọ bụ ndị na-ewu ahụ. Onye na-ere ahịa na-ekwu na ihe a nwere ike imeziwanye arụmọrụ na ọnụ ọgụgụ kasị elu nke ọzụzụ. Onye na-ere ahịa na-ekwu na nke a dabere na "nchọpụta na-egosi na oke amonia nwere ike jikọta na α- Ketoglutaric acid wepụrụ iji belata ọtụtụ nsogbu nke nsị amonia kpatara. Otú ọ dị, o gosiri na α- Naanị ihe ọmụmụ dị irè na ketoglutarate na-ebelata amonia. nsị bụ naanị maka ndị ọrịa nwetara hemodialysis.
| Ihe | Nkọwapụta | Nsonaazụ |
| Njirimara | kristal ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha ma ọ bụ kristal ntụ ntụ | kristal ọcha |
| Ebe mgbaze | 113 ~ 117 ℃ | 114-116 ℃ |
| Fe | ≤10ppm | Dabara |
| nnyefe | ≥97% | 98.4% |
| Ọnwụ na ihicha | ≤0.5% | 0.12% |
| Ihe fọdụrụ na mgbanye | ≤0.2% | 0.02% |
| Igwe dị arọ | ≤10ppm | Dabara |
| Nyocha | ≥99% | 99.48% |
| Mmechi | Nsonaazụ dabara n'ụkpụrụ ụlọ ọrụ | |
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