Azelaic acid ntụ ntụ , dị ka acid dicarboxylic jupụtara n'okike, adọtala mmasị dị ukwuu na ngwaahịa nlekọta anụ ahụ n'afọ ndị na-adịbeghị anya. Na mgbakwunye na mmetụta dị ịrịba ama ya n'ịgwọ ihe otutu na ịhazi pigmentation, azelaic acid na-egosipụtakwa àgwà ndị ọzọ ama ama. Dị ka ihe antioxidant, ọ nwere ike inyere akpụkpọ ahụ aka ịlụ ọgụ megide mmebi radical free, na-echekwa ahụike anụ ahụ na ntorobịa. Tụkwasị na nke ahụ, egosila na azelaic acid nwere mmetụta mgbochi mkpali ma nwee ike ibelata nsị anụ ahụ, na-eme ka ọ dị mma maka ndị nwere akpụkpọ anụ na ụdị akpụkpọ anụ nke na-acha uhie uhie. Ọdịdị molekụla ya pụrụ iche na-eme ka ọ bụrụ ihe magburu onwe ya n'ịhazi pigmenti akpụkpọ anụ na imezi ụda akpụkpọ ahụ na-enweghị isi. N'ozuzu, azelaic acid, dị ka ihe na-ahụ maka nlekọta anụ ahụ multifunctional, na-enye nchebe zuru oke na nrụzi maka akpụkpọ ahụ, ọ bụkwa otu n'ime ihe ndị dị mkpa na-asọpụrụ nke ukwuu na ngwaahịa nlekọta anụ ahụ.
1. Isi mmalite na njirimara nke Azelaic acid
Isi mmalite:
(1). Ọka wit na ọka bali: Azelaic acid nwere ike ịpụta na ọka wit na ọka bali. Mkpụrụ ọka ndị a nwere ụfọdụ Azelaic Acid, nke enwere ike nweta site na ụzọ mmịpụta kpọmkwem.
(2). Humic acid: Azelaic acid dịkwa na humic acid. Humic acid bụ ihe sitere n'okike nke a na-ahụkarị na gburugburu eke dị ka ala, peat na peat, nwere ụfọdụ Azelaic Acid.
(3). Fungal gbaa ụka: na mgbakwunye na isi mmalite eke;98% Azelaic acid nwekwara ike synthesized site gbaa ụka usoro nke dịkwa ka usoro ha. N'ime ụlọ nyocha, fungi nwere ike ịtụgharị mkpụrụ osisi a kapịrị ọnụ ka ọ bụrụ Azelaic Acid, si otú a na-emepụta Azelaic Acid dị ọcha.
(4). Ngwakọta kemịkalụ: Na mgbakwunye, Azelaic Acid nwekwara ike ịkwado site na usoro njikọ kemịkal. Site n'iji ụzọ mmeghachi omume kemịkalụ akọwapụtara, Azelaic Acid nwere otu nhazi na akụrụngwa nwere ike ịmekọrịta.
njirimara:
(1). Njirimara antioxidant: Azelaic acid nwere ihe antioxidant, nke nwere ike inyere akpụkpọ ahụ aka iguzogide mbuso agha nke radicals efu ma belata ịka nká na mmebi nke mmeghachi omume oxidative kpatara.
(2). Mmetụta mgbochi mkpali: E gosiputara na ihe a nwere mmetụta mgbochi mkpali, nke nwere ike ibelata nsị anụ ahụ, belata ọbara ọbara, ọzịza, na ahụ erughị ala. Ọ dị mma maka ndị nwere akpụkpọ anụ na ụdị akpụkpọ anụ nke na-adịkarị na-acha uhie uhie.
(3). Mmetụta nje na-egbochi nje: A na-eji Azelaic acid eme ihe n'ọtụtụ ebe n'ịgwọ ihe otutu na ihe otutu, n'ihi na ọ nwere ike ibelata ọnụ ọgụgụ nje bacteria na elu akpụkpọ ahụ, belata mbufụt, ma belata keratinization ntutu isi.
(4). Na-achịkwa pigmentation: Azelaic acid nwere ike itinye aka na njikọ nke melanin, na-enyere aka igbochi mmepụta nke melanin, belata oke pigmenti, ma melite ụda akpụkpọ ahụ na-adịghị mma na okwu pigmentation.
(5). Nnukwu mgbanwe:Azelaic aciddabara maka ụdị anụ ahụ dị iche iche, gụnyere akpụkpọ mmanu mmanu, akpụkpọ anụ kpọrọ nkụ, na akpụkpọ ahụ dị nro, ma nwee ezigbo nnabata.
(6). Ịdị nwayọọ: Tụnyere ihe ndị ọzọ a na-eji agwọ ihe otutu, dị ka benzoic acid na benzoyl peroxide, Azelaic Acid enwechaghị mgbakasị ahụ yana ịdị nwayọọ dị elu.
2. Mmetụta ọgwụgwọ na ihe otutu na ihe otutu
(1). Mmetụta nje bacteria: Azelaic Acid nwere mmetụta antibacterial, karịsịa na Propionibacterium acnes, nke na-ebute ihe otutu. Site n'ibelata ọnụ ọgụgụ nje bacteria n'elu akpụkpọ ahụ, Azelaic Acid nwere ike ibelata mbufụt ma belata nhazi nke otutu na otutu.
(2). Na-achịkwa stratum corneum:Azelaic acid buru ibu nwere ike ịkwalite metabolism nkịtị nke stratum corneum, belata keratinization na oghere ntutu isi, ma nyere aka gbochie mgbochi ntutu isi na ihe otutu. Ọ nwekwara ike ibelata nguzobe nke isi ojii na pimples.
(3). Mmetụta mgbochi mkpali: Azelaic Acid nwere ihe mgbochi mkpali, nke nwere ike ibelata nzaghachi mkpali nke akpụkpọ ahụ, belata ọbara ọbara, ọzịza, mgbu, na ahụ erughị ala na ihe otutu na ihe otutu.
(4). Na-achịkwa pigmentation: Mgbe ọgwụgwọ nke ihe otutu na ihe otutu, ọ dị mfe ịhapụ pigmentation, na Azelaic Acid nwere ike itinye aka na njikọ nke melanin, na-enyere aka belata nguzobe nke pigmenti ma melite ụda akpụkpọ ahụ na-enweghị isi.
(5). Mgbochi nke nlọghachite: N'ihi mmetụta zuru oke nke Azelaic Acid, ọ bụghị naanị na ọ na-agwọ ihe otutu na acne dị ugbu a, kamakwa igbochi ihe ọhụụ ọhụrụ, na-achịkwa nke ọma nlọghachi nke otutu.
3. Hazie pigmenti na ụda akpụkpọ ahụ na-adịghị mma
(1). Mgbochi nke njikọ melanin: Azelaic acid egosila na ọ na-etinye aka na nhazi nke melanin. Melanin bụ otu n'ime isi ihe na-eduga n'ọcha akpụkpọ ahụ. Site na igbochi njikọ nke melanin, azelaic acid nwere ike ibelata ntinye nke melanin n'elu akpụkpọ ahụ, si otú ahụ na-eme ka nsogbu dị ka pigmentation na freckles, na-eme ka ụda akpụkpọ ahụ dịkwuo elu.
(2). Kwalite stratum corneum metabolism: Azelaic acid na-enyere aka ịkwalite metabolism nkịtị nke stratum corneum akpụkpọ. Metabolism na-adịghị mma nke stratum corneum nwere ike iduga ụda akpụkpọ anụ, ebe azelaic acid nwere ike mee ka mwụsị keratin ochie na nke nwụrụ anwụ dị ngwa, kwalite metabolism, mee ka akpụkpọ ahụ dịkwuo nro na nke siri ike karị, ma nyere aka melite nsogbu nke ụda akpụkpọ ahụ.
(3). Njirimara Antioxidant: Azelaic Acid nwere mmetụta antioxidant ụfọdụ ma nwee ike inyere akpụkpọ ahụ ọgụ megide mmebi nke radicals efu kpatara. Free radicals bụ otu n'ime ihe ndị dị mkpa na-eduga n'ịka nká akpụkpọ. Antioxidants nwere ike kwụsịlata radicals efu, belata mmebi akpụkpọ ahụ ha, nyere aka ịnọgide na-eto eto na ahụ ike, na-ebelata ọdịdị nke ụda akpụkpọ ahụ.
(4). Mgbochi nke mmeghachi omume mkpali: Akwupụtakwara na Azelaic Acid nwere mmetụta mgbochi mkpali, nke nwere ike ibelata mbufụt akpụkpọ. Mmeghachi omume nfụkasị ahụ nwere ike ọ bụghị nanị na-ebute ọbara ọbara na ọzịza nke akpụkpọ ahụ, ma ọ pụkwara iduga na pigmenti. Site na igbochi mmeghachi omume mkpali, azelaic acid na-enyere aka belata nguzobe nke pigmenti ma melite ụda akpụkpọ ahụ gbara ọchịchịrị.
4. Antioxidant na mgbochi mkpali mmetụta
(1). Mmetụta Antioxidant: Dị ka antioxidant, azelaic acid nwere ikike iwepụ radicals efu. radicals free bụ ụmụ irighiri ihe na-adịghị akwụsi ike nke nwere ike ibute mmebi oxidative na mkpụrụ ndụ akpụkpọ anụ na anụ ahụ jikọtara, na-eduga na ịka nká akpụkpọ, pigmentation na nsogbu ndị ọzọ. Azelaic acid nwere ike imeghachi omume na radicals n'efu iji kwụsị ọrụ ha, si otú ahụ belata mmebi nke radicals free na akpụkpọ ahụ ma na-egbu oge usoro ịka nká nke akpụkpọ ahụ.
(2). Mmetụta mgbochi mkpali: Adipic acid na-arụ ọrụ mgbochi mkpali site na igbochi mmepụta na ntọhapụ nke ihe ndị na-egbuke egbuke. Mbufụt bụ ihe na-ebutekarị ọrịa anụ ahụ na ihe mgbaàmà, dị ka ihe otutu na ihe otutu. Azelaic acid nwere ike ibelata mmeghachi omume mkpali, belata mgbaàmà dị ka acha ọbara ọbara, ọzịza, itching, na mgbu, ma nyere aka melite ọrịa akpụkpọ anụ ahụ.
(3). Na-achịkwa metabolism cell epidermal: Azelaic acid nwere ike ịkwalite metabolism nkịtị nke sel epidermal, melite nhazi na ọrụ nke stratum corneum, ma welie ikike nrụzi anụ ahụ. Nke a na-enyere aka belata ihe omume na mmụba nke mbufụt na-adịghị ala ala, si otú ahụ belata mmebi nke nsị na-adịghị ala ala na akpụkpọ ahụ.
(4). Azelaic acid nwere ike ibelata mmeghachi ahụ nfụkasị ahụ, nke nwekwara ike ibelata oke iwe anụ ahụ na ihe ndị na-eri ahụ ma nyere aka belata mgbaàmà anụ ahụ. Site na ibelata mmeghachi omume nfụkasị ahụ, azelaic acid nwere ike belata mgbasa nke mbufụt na akpụkpọ ahụ ma belata mmetụta nke nsị na akpụkpọ ahụ.
Kedu ihe kpatara ịhọrọ ngwaahịa nlekọta anụ ahụ nwere Azelaic Acid?
(1). Mmetụta ịcha ọcha na ntụpọ ntụpọ:Azelaic acid capsules nwere ike itinye aka na njikọ nke melanin ma kwalite stratum corneum metabolism, na-enyere aka belata pigmentation na freckles, na-eme ka ụda akpụkpọ ahụ dịkwuo ọkụ ma na-egbuke egbuke. Ịhọrọ ngwaahịa nlekọta anụ ahụ nwere Azelaic Acid nwere ike inye aka melite ụda akpụkpọ ahụ na okwu pigmenti.
(2). Mgbochi na-egbu egbu na mmetụta ịhịa aka n'ahụ: Azelaic Acid nwere mmetụta mgbochi mkpali, nke nwere ike ibelata nsị anụ ahụ ma nyere aka belata nsogbu na akpụkpọ anụ dị nro na ihe otutu. Ịhọrọ ngwaahịa nlekọta anụ ahụ nwere Azelaic Acid nwere ike inye aka mee ka akpụkpọ ahụ dị jụụ, belata ọbara ọbara, ọzịza, na itching.
(3). Nchedo Antioxidant: Azelaic Acid bụ antioxidant dị irè nke nwere ike iwepụ mmebi sitere na radicals efu ma belata mmebi gburugburu ebe obibi na akpụkpọ ahụ. Ịhọrọ ngwaahịa nlekọta anụ ahụ nwere Azelaic Acid nwere ike inyekwu nchebe antioxidant ma na-egbu oge usoro ịka nká nke akpụkpọ ahụ.
(4). Imezi nsogbu ihe otutu: A na-eji Azelaic Acid na-agwọ nsogbu ọnya, yana ọgwụ nje na mgbochi mkpali na-enyere aka belata ọnya ihe otutu ma gbochie nlọghachi nke otutu. Ịhọrọ ngwaahịa nlekọta anụ ahụ nwere Azelaic Acid nwere ike inye aka melite akpụkpọ ahụ na-adịkarị mfe ma sachaa pores.
(5). Na-achịkwa nzuzo nzuzo nke mmanụ: Azelaic acid na-ekerekwa òkè n'ịchịkwa ihe nzuzo nke mmanụ, nke na-enyere aka ịchịkwa mmanu akpụkpọ ahụ nke na-akpata oke mmiri ozuzo. Ịhọrọ ngwaahịa nlekọta anụ ahụ nwere Azelaic Acid nwere ike ime ka nguzozi mmanụ na mmiri akpụkpọ ahụ dịkwuo mma ma melite ọnọdụ akpụkpọ ahụ nwere mmanu mmanu.
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Oge nzipu: Mar-21-2024