PQQ ọ dị mma karịa CoQ10?
Okwu mmalite:
N'akụkụ ihe mgbakwunye, antioxidants na-arụ ọrụ dị oke mkpa n'ịkwalite ahụike na ike zuru oke. Abụọ ndị isi egwuregwu n'ọgbọ egwuregwu a bụPQQ (Pyrroloquinoline quinone)naCoQ10 (Coenzyme Q10) . Ha abụọ bụ ndị a ma ama maka ikike ha nwere ịkwado ahụike cellular na ịlụso nrụgide oxidative ọgụ. Ma olee onye na-achị kacha elu? Ka anyị lebakwuo anya na ajụjụ a wee kpughee ihe omimi nke antioxidants.
Ịghọta Antioxidants:
Tupu anyị atụlee PQQ na CoQ10, ọ dị mkpa ịghọta mkpa antioxidants. Ngwakọta ndị a na-ewepụ ihe ndị na-akpata free radicals, nke bụ ụmụ irighiri ihe na-emerụ ahụ nke nwere ike imebi mkpụrụ ndụ ma tinye aka na ịka nká na ọrịa. Site n'ịchụpụ radicals efu, antioxidants na-enyere aka ichebe mkpụrụ ndụ pụọ na nrụgide oxidative ma na-edobe ịdị mma n'ozuzu ya.
PQQ: Onye bịara ọhụrụ nwere ike:
PQQ ntụ ntụ adọtara uche n'afọ ndị na-adịbeghị anya maka ihe onwunwe ya pụrụ iche. Ọ na-arụ ọrụ dị ka cofactor redox ma na-ekere òkè na ụzọ mgbaàmà ekwentị, n'ikpeazụ na-akwalite biogenesis mitochondrial. Nke a pụtara na PQQ nwere ike ịkwalite mmepụta ume cell ma kwado ọrụ mitochondrial zuru oke, nke dị oke mkpa maka ahụike na ike dị mma.
1. Usoro antioxidant nkePyrroloquinoline Quinone ntụ ntụ Pqq ntụ ntụ:
PQQ (Pyroquinoline Quinone) bụ antioxidant siri ike, yana usoro antioxidant ya bụ isi gụnyere:
- Na-eme ka radicals efu:PQQ nwere ike imeghachi omume na radicals efu iji mee ka ụmụ irighiri ihe ndị a na-arụ ọrụ nke ukwuu ma belata mmebi ha na sel.
- Na-akwalite ọrụ enzyme antioxidant:Nnyocha egosiwo naPyrroloquinoline Quinone Disodium nnunwere ike ịkwalite ọrụ nke enzymes antioxidant, dị ka superoxide dismutase (SOD) na glutathione peroxidase (GPx), na-eme ka ikike antioxidant nke mkpụrụ ndụ dịkwuo elu.
- Na-echebe mitochondria: Mitochondria bụ isi saịtị maka mmepụta ume n'ime sel yana ebumnuche bụ isi nke nrụgide oxidative. PQQ na-egosipụta mmetụta antioxidant na-apụtaghị ìhè site na ichebe mitochondria site na mmebi oxidative, na-akwalite ọrụ ha.
2.Tụnyere n'etiti PQQ na ndị ọzọ antioxidants:
- Tụnyere CoQ10 : PQQ, PQQ nwere bioavailability dị elu ma nwee ike ịrụ ọrụ nke ọma n'ihe gbasara akụrụngwa antioxidant. Ọzọkwa, PQQ nwere ike ịkwalite ọgbọ mitochondrial ma nyekwuo ike maka mkpụrụ ndụ.
- Tụnyere vitamin C na vitamin E : Ọ bụ ezie na PQQ na Vitamin C na Vitamin E bụ ma antioxidants dị ike, usoro ọrụ ha na mmetụta ha dịtụ iche. PQQ na-etinye aka na nhazi akara ekwentị na ọrụ mitochondrial, ma e jiri ya tụnyere vitamin C na E, PQQ nwere ike inwe mmetụta antioxidant zuru oke.
CoQ10: Onye meriri emebere:
N'aka nke ọzọ, Coenzyme Q10 ka a na-eto ogologo oge dị ka antioxidant ụlọ ike. Ọ na-arụ ọrụ dị mkpa na agbụ ụgbọ njem elektrọn, na-eme ka mmepụta ATP dị mfe ma na-enye ike cellular. Na mgbakwunye, CoQ10 na-arụ ọrụ dị ka antioxidant siri ike, na-echebe mkpụrụ ndụ site na mmebi oxidative na ịkwado ahụike obi.
- Neutralizing free radicals: Otu n'ime isi ọrụ nke coenzyme Q10 ntụ ntụ n'ime sel bụ iji kpochapụ radicals free ma belata mmebi nke nrụgide oxidative na sel. Free radicals bụ ụmụ irighiri ihe na-arụsi ọrụ ike nke ukwuu nwere otu eletrọn na-emekọghị ọnụ nke na-emeghachi omume na macromolecules dị ndụ n'ime sel, dị ka protein, lipids, na DNA, na-eduga na mmebi cell na ịka nká. Coenzyme Q10 na-ewepụ radicals n'efu site n'inye electrons, na-ebelata mmebi ha na sel.
- Na-eme ka ihe ndị ọzọ na-eme ka ọ dịghachi ndụ: Coenzyme Q10 nwekwara ike ịmaliteghachi ihe ndị ọzọ na-eme ka ọ dịghachi ndụ, dị ka vitamin E, na-emegharị ya na ịkwalite mmetụta antioxidant ya.
- Chebe ọrụ mitochondrial: Mitochondria bụ ebe nrụpụta ike n'ime sel yana otu n'ime ebumnuche kachasị nke nrụgide oxidative. Coenzyme Q10 na-ekere òkè na usoro mbufe elektrọn nke mitochondrial respiratory chain, na-enyere aka ịmepụta ike nke mkpụrụ ndụ chọrọ ma na-echebe mitochondria site na mmebi oxidative, na-ejigide ọrụ ha.
- Mbelata nrụgide oxidative: Mmetụta antioxidant nke coenzyme Q10 nwere ike ibelata ọkwa nrụgide oxidative, na-echekwa nguzozi redox cellular, nyere aka gbochie mmebi cell na ịka nká nke nrụgide oxidative kpatara, wee si otú ahụ chebe ahụike.
Nyocha atụnyere:
Mgbe ị na-atụnyere PQQ na CoQ10, ọtụtụ ihe na-abata:
- Bioavailability: A maara CoQ10 nke ọma maka bioavailability ya na-adịghị mma, nke pụtara na ahụ nwere ike ọ gaghị etinye akụkụ dị ukwuu nke ọma. N'ụzọ dị iche, PQQ na-egosipụta bioavailability dị elu, nke nwere ike ibute uru ahụike ndị ọzọ.
- Nkwado Mitochondrial: AbụọPqq Pyrroloquinoline Quinone ntụ ntụ na CoQ10 na-arụ ọrụ dị mkpa n'ịkwado ọrụ mitochondrial. Agbanyeghị, ikike PQQ nwere ịkwalite mitochondrial biogenesis na-ekewa ya iche, na-atụ aro uru sara mbara maka mmepụta ike ekwentị yana ike zuru oke.
- Mmetụta mmekọrịta: Ụfọdụ ọmụmụ na-atụ aro na PQQ na CoQ10 nwere ike inwe mmetụta synergistic mgbe ejikọtara ọnụ. Site n'ilekwasị anya n'akụkụ dị iche iche nke ahụike cellular, antioxidants ndị a nwere ike ịkwado ibe ha ma nyekwa uru bara uru.
Mmechi:
Na arụmụka n'etiti PQQ na CoQ10, ọ dịghị onye mmeri doro anya. Onye ọ bụla antioxidant na-enye uru pụrụ iche ma nwee ike dabara maka ndị dị iche iche dabere na ebumnuche na mkpa ahụike ha. Ọ bụ ezie na CoQ10 nwere aha dị ogologo dị ka antioxidant siri ike, PQQ na-apụta dị ka onye bịara ọhụrụ na-ekwe nkwa nke nwere uru ndị nwere ike ime n'ihe gbasara bioavailability na nkwado mitochondrial.
N'ikpeazụ, nhọrọ n'etiti PQQ na CoQ10 nwere ike ịdabere na mmasị onye ọ bụla na echiche ahụike. Maka ndị na-achọ nkwado antioxidant zuru oke, ijikọta ihe mgbakwunye abụọ a nwere ike ịbụ atụmatụ amamihe iji jikwa mmetụta synergistic na ịbawanye ahụike cellular.
Ụlọ ọrụ Xi'an tgybio Biotech Co.,LTDPQQ ntụ ntụ na Coenzyme Q10 ntụ ntụ soplaya, anyị nwere ike ịnyePQQ Capsules / PQQ MmejunaCoenzyme Q10 Capsules / Coenzyme q10 Mmeju . Ụlọ ọrụ anyị na-akwado OEM/ODM Otu nkwụsị ọrụ, gụnyere ngwugwu ahaziri ahazi na akara. Ọ bụrụ na ị nwere mmasị, ị nwere ike izipu ozi-e na yarebecca@tgybio.comma ọ bụ WhatsApp +8618802962783.
Ntụaka:
- Harris, CB, Chowanadisai, W., Mishchuk, DO, & Satre, MA (2013). Pyrroloquinoline quinone (PQQ) na-ebelata peroxidation lipid ma kwalite ọrụ mitochondrial na ụbụrụ oke na mitochondria imeju. Mitochondion, 13 (6), 336-342.
- Littaru, GP, & Tiano, L. (2007). Njirimara bioenergetic na antioxidant nke coenzyme Q10: mmepe na-adịbeghị anya. Biotechnology Molecular, 37(1), 31-37.
- Nakano, M., Ubukata, K., Yamamoto, T., & Yamaguchi, H. (2009). Mmetụta nke pyrroloquinoline quinone (PQQ) na ọnọdụ uche nke ndị agadi na ndị agadi. Ụdị nri, 21 (13), 50-53.