Fisetin ntụ ntụ bụ ngwakọta flavonoid eke nke dị na mkpụrụ osisi na akwụkwọ nri. Dị ka molekul nwere ike ime ihe, Fisetin adọtala uche zuru oke na mpaghara sayensị. Ọdịdị kemịkal ya nwere ọtụtụ hydroxyl dị iche iche, nke na-eme ka ọ nwee ezigbo ihe antioxidant. Nnyocha egosiwo na Fisetin nwere ike ịrụ ọrụ ndụ site n'ịhazi ọtụtụ ụzọ mgbaàmà, na-emetụta usoro dịka okirikiri cell na apoptosis. Agbanyeghị, achọrọ nyocha ọzọ na bioavailability na pharmacokinetics nke Fisetin iji kpughee usoro ọrụ ya na ahụ mmadụ. Agbanyeghị, okwu gbasara ma oriri Fisetin kwa ụbọchị ọ dị mma nlebara anya nke ukwuu. Edemede a ga-enyocha usoro nchekwa nke oriri Fisetin kwa ụbọchị site n'echiche dị iche iche.
Kedu ihe bụ Fisetin?
Fisetin bụ ngwakọta flavonoid eke, nke sitere na ụdị nke ogige flavonoid. Ọ dị n'ọtụtụ osisi, dị ka apụl, strawberries, lemons, a hụkwara ya na nri ndị dị ka eyịm na kukumba. N'ikwu okwu kemịkalụ, Fisetin bụ flavonoid nwere nhazi nke mgbanaka benzene abụọ na otu heterocycle, nwere ọtụtụ otu hydroxyl. Ihe owuwu hydroxyl ndị a na-enye Fisetin nwere ezigbo antioxidant Njirimara.
Fisetin adọtala nlebara anya zuru ebe niile site n'aka ndị sayensị n'ihi nhazi kemịkalụ pụrụ iche na ọrụ ndụ ya. Nnyocha egosila na Fisetin nwere ike inwe mmetụta nchịkwa na usoro ndu dị ka okirikiri cell na apoptosis, ebe ọ na-enwekwa ụfọdụ ihe omume ndu. Na vivo, Fisetin nwere ike rụpụta mmetụta ya site n'ịhazi ọtụtụ ụzọ mgbaàmà, mana nyocha ọzọ gbasara bioavailability ya na ọgwụ ọgwụ dị mkpa iji kpughee usoro ya n'ime ahụ mmadụ. N'ozuzu, dị ka ihe sitere n'okike, Fisetin nwere usoro kemịkal pụrụ iche na ọrụ ndu, na usoro ya na-eme n'ime ahụ mmadụ kwesịrị nyocha ọzọ.
Uru Fisetin Powder
1. Mmetụta antioxidant nke Fisetin
98% Fisetinbụ ngwakọta flavonoid eke nwere ezigbo antioxidant Njirimara.
(1). Ọdịdị kemịkal nke Fisetin
Fisetin bụ ngwakọta flavonoid sitere n'okike nwere usoro ihe omimi C ₁æ H ₁₀O ₆. O nwere otutu ihe owuwu hydroxyl, gụnyere otu hydroxyl na mgbanaka aromatic ya.
(2). Na-anọpụ iche free radicals
Free radicals bụ ụmụ irighiri ihe na-adịghị akwụsi ike na-achọ electrons site na ụmụ irighiri ihe ndị ọzọ ka ha kwụsie ike, na-eduga na mmebi oxidative. Ọdịdị hydroxyl n'ime98% Fisetin ntụ ntụnwere ike inye electrons na free radicals, wepụ ọrụ ha, wee si otú ahụ belata mmebi oxidative nke mkpụrụ ndụ.
(3). Mwepụ nke ihe na-egbu egbu na-arụ ọrụ
Dị ka antioxidant, Fisetin nwere ike iwepụ oxidants na-arụ ọrụ dịka anions superoxide, hydrogen peroxide, na hydroxyl radicals. Site na mmetụta mkpochapụ a, Fisetin nwere ike ibelata mmebi cellular nke nrụgide oxidative kpatara.
(4). Mgbochi nke ọrụ oxidase
Fisetin nwekwara ike igbochi ọrụ ụfọdụ oxidase enzymes, dị ka peroxidase na oxidoreductase, si otú ahụ na-ebelata ọganihu nke mmeghachi omume oxidative n'ime ahụ ma na-ebelata ogo nke nrụgide oxidative.
(5). Na-akwalite ọrụ enzyme antioxidant
Nnyocha egosila na Fisetin nwere ike ịkwalite ọrụ enzyme antioxidant dị mkpa, dị ka superoxide dismutase (SOD) na glutathione peroxidase (GPx), iji nyere mkpụrụ ndụ aka ịnagide nrụgide oxidative nke ọma.
(6). Mmetụta zuru oke
N'ozuzu, usoro antioxidant nkeFisetin nnukwugụnyere inye electrons iji kwụsị radicals n'efu, ikpochapụ oxidants na-arụ ọrụ, igbochi ọrụ oxidase, na ịkwalite ọrụ enzyme antioxidant, n'etiti ụzọ ndị ọzọ, iji jikọta mmetụta antioxidant ma chebe mkpụrụ ndụ pụọ na mmebi oxidative.
2. Mmetụta mgbochi mkpali nke Fisetin
A na-ahụtakwa Fisetin ka ọ nwere mmetụta mgbochi mkpali dị ịrịba ama, na-enyere aka belata mmeghachi omume mkpali.
(1). Na-ahazi ụzọ mgbama mkpali
Fisetin na-arụ ọrụ mgbochi mkpali site na-emetụta ọrụ nke ọtụtụ ụzọ mgbaàmà mkpali. Ọ nwere ike ịhazigharị NF-κ B. MAPK na ụzọ mgbaàmà STAT na-egbochi okwu nke mkpụrụ ndụ ihe nketa metụtara mbufụt, si otú ahụ belata ihe omume na nnọgidesi ike nke mmeghachi omume mkpali.
(2). Na-egbochi ntọhapụ nke ndị ogbugbo mkpali
Nnyocha egosila naFisetin ntụ ntụ dị ọchanwere ike igbochi ntọhapụ nke ndị ogbugbo mkpali, dị ka tumor necrosis factor- α (TNF) - α）, Interleukin-1 β (IL-1) β） Na interleukin-6 (IL-6), wdg. ọrụ dị mkpa na nzaghachi mkpali, na mgbochi nke Fisetin na-enyere aka belata oke mbufụt.
(3). Belata ịgbalite sel mkpali
Fisetin nwere ike ibelata ọrụ na ntinye nke mkpụrụ ndụ ndị na-egbu egbu (dịka macrophages, lymphocytes, na neutrophils), na-ebelata ogo nke mkpụrụ ndụ mkpali na-ahapụ ndị mgbasa ozi mkpali, wee si otú a belata mmebi anụ ahụ nke mmeghachi omume mkpali kpatara.
(4). Na-egbochi okwu nke protein metụtara mbufụt
Fisetin nwekwara ike igbochi nkwupụta nke ụfọdụ protein metụtara mbufụt, dị ka inducible nitric oxide synthase (iNOS) na cyclooxygenase-2 (COX-2), nke na-arụ ọrụ dị mkpa na usoro mkpali. Site na igbochi okwu ha, Fisetin na-enyere aka ịchịkwa nzaghachi mkpali.
(5). Ngwakọta nke antioxidant na mgbochi mkpali mmetụta
Ọ dị mma ịmara na mmetụta antioxidant nke Fisetin na-enyekwa aka na mmetụta mgbochi mkpali ya. Njirimara antioxidant nwere ike ibelata mmebi nke nrụgide oxidative na sel, si otú a na-ebelata ihe ndị na-adịghị ahụkebe nke mmeghachi omume mkpali ma na-ebelata ogo nke mbufụt.
3. Nchebe nke usoro ụjọ ahụ
(1). Nchekwa neuron
Nnyocha egosila naFisetin 98% nwere ike ịkwalite uto na mmepe nke neuronal, ma nwee mmetụta nchebe na neurons. Ọ na-enyere aka ịnọgide na-enwe ọnọdụ ahụike nke neurons, na-egbu oge nkwụsị nke neuronal, ma nwee mmetụta nchebe na usoro ụjọ ahụ.
(2). Usoro nchịkwa akwara
Ụfọdụ ọmụmụ na-egosi na Fisetin nwere ike inye aka melite ọrụ nchịkwa akwara, kwalite ntọhapụ nke neurotransmitters na ntụgharị mgbaàmà akwara, si otú ahụ na-eme ka ọnọdụ ọrụ nke usoro ụjọ ahụ dịkwuo mma.
(3). Iwu nke mkpụrụ ndụ ihe nketa neuroprotective
Fisetin nwere ike ịkwalite nchebe na nrụzi nke usoro ụjọ ahụ site n'ịchịkwa okwu nke ụfọdụ mkpụrụ ndụ ihe nketa na-adịghị ahụkebe, dị ka BDNF (ụbụrụ neurotrophic kpatara ụbụrụ).
Nchekwa nke oriri Fisetin kwa ụbọchị
(1). Nchọpụta nnwale anụmanụ
Nnwale ụmụ anụmanụ egosila na ị rie Fisetin agafeghị oke na-adịkarị mma ma ọ nweghị mmetụta ọ bụla na-egbu egbu ahụbeghị. Otú ọ dị, ekwesịrị iburu n'uche na a pụghị ịkọwapụta nsonaazụ nke nnwale anụmanụ na ụmụ mmadụ.
(2). dose na onye iche iche
Mmeghachi omume n'otu n'otu na Fisetin nwere ike ịdịgasị iche, yana a na-atụ aro ka ị gbasoo usoro ọgwụgwọ ndị nrụpụta tụrụ aro mgbe ị na-aṅụ Fisetin wee nyochaa mmeghachi omume anụ ahụ nke onye ọ bụla.
Ọ bụ ezie na Fisetin nwere ọtụtụ uru ahụike nwere ike ime, a chọkwuru nyocha sayensị iji kwado nchekwa nke oriri Fisetin kwa ụbọchị. Ndị na-azụ ahịa kwesịrị iji nlezianya tụlee oriri Fisetin ha na-eri kwa ụbọchị ma mee mkpebi dabere na ọnọdụ onwe onye. A na-atụ aro ka iji Fisetin n'okpuru nduzi nke dọkịta na-ahụ maka iji hụ na nchekwa na ịdị irè.
Xi'an tgybio Biotech Co., Ltd bụ fisetin ntụ ntụ emeputa, anyị nwere ike na-enyefisetin capsulesma ọ bụihe mgbakwunye fisetin , Anyị nwere ndị otu ọkachamara na-enyere gị aka ịmepụta nkwakọ ngwaahịa na akara, gụnyere nchịkọta ahaziri aha na aha. Webiste anyị bụ /. Ọ bụrụ na ị nwere mmasị, ị nwere ike izipu ozi-e rebecca@tgybio.com ma ọ bụ WhatsAPP +86 18802932783.
Oge nzipu: Mar-19-2024
