Fisetin Foda wani fili na flavonoid ne na halitta wanda ke da yawa a cikin 'ya'yan itatuwa da kayan marmari. A matsayin yuwuwar kwayoyin halitta, Fisetin ya jawo hankalin jama'a a cikin al'ummar kimiyya. Tsarin sinadaransa ya ƙunshi ƙungiyoyin hydroxyl da yawa, wanda ya sa ya sami kyawawan kaddarorin antioxidant. Bincike ya nuna cewa Fisetin na iya yin aikin ilimin halitta ta hanyar daidaita hanyoyin sigina da yawa, yana shafar matakai kamar tsarin tantanin halitta da apoptosis. Koyaya, ana buƙatar ƙarin bincike akan bioavailability da pharmacokinetics na Fisetin don bayyana tsarin aikinsa a cikin jikin ɗan adam. Koyaya, batun ko shan Fisetin na yau da kullun yana da lafiya ya sami kulawa sosai. Wannan labarin zai bincika cikin tsari cikin tsari na amincin shan Fisetin na yau da kullun ta fuskoki daban-daban.
Menene Fisetin?
Fisetin wani fili ne na flavonoid na halitta, na cikin nau'in mahadi na flavonoid. Yana samuwa a cikin tsire-tsire masu yawa, kamar apples, strawberries, lemo, kuma ana samunsa a cikin abinci irin su albasa da cucumbers. Maganar sinadarai, Fisetin flavonoid ne mai tsari na zoben benzene guda biyu da kuma keken keke guda ɗaya, wanda ya ƙunshi ƙungiyoyin hydroxyl da yawa. Waɗannan sifofin hydroxyl suna ba Fisetin tare da kyawawan kaddarorin antioxidant.
Fisetin ya jawo hankalin jama'a da yawa daga masana kimiyya saboda tsarin sinadarai na musamman da kuma ayyukan nazarin halittu. Bincike ya nuna cewa Fisetin na iya samun tasiri na tsari akan hanyoyin nazarin halittu irin su sake zagayowar tantanin halitta da apoptosis, yayin da kuma ya mallaki wasu ayyukan ilimin halitta. A cikin vivo, Fisetin na iya yin tasirinta ta hanyar daidaita hanyoyin sigina da yawa, amma ana buƙatar ƙarin bincike kan bioavailability da pharmacokinetics don bayyana tsarin aikinsa a cikin jikin ɗan adam. Gabaɗaya, a matsayin wani fili na halitta, Fisetin yana da tsarin sinadarai na musamman da kuma ayyukan nazarin halittu, kuma tsarin aikinsa a cikin jikin ɗan adam ya cancanci ƙarin bincike.
Amfanin Foda na Fisetin
1. Sakamakon antioxidant na Fisetin
98% Fisetinwani fili flavonoid ne na halitta tare da kyawawan kaddarorin antioxidant.
(1). Tsarin sinadaran Fisetin
Fisetin wani fili ne na flavonoid na halitta tare da tsarin kwayoyin C ₁æ H ₁₀O ₆. Ya ƙunshi tsarin hydroxyl da yawa, gami da ƙungiyoyin hydroxyl akan zobensa na kamshi.
(2). Neutralizing free radicals
Free radicals su ne marasa ƙarfi kwayoyin da ke neman electrons daga wasu kwayoyin halitta don daidaita kansu, haifar da lalacewar oxidative. Tsarin hydroxyl a cikin98% Fisetin Fodana iya ba da gudummawar electrons zuwa ga radicals kyauta, kawar da ayyukansu, don haka rage lalacewar oxidative ga sel.
(3). Cire abubuwan oxidizing masu aiki
A matsayin antioxidant, Fisetin na iya kawar da oxidants masu aiki kamar su superoxide anions, hydrogen peroxide, da hydroxyl radicals. Ta hanyar wannan sakamako na sharewa, Fisetin na iya rage lalacewar salula wanda ya haifar da damuwa.
(4). Hana ayyukan oxidase
Fisetin kuma zai iya hana ayyukan wasu enzymes oxidase, irin su peroxidase da oxidoreductase, don haka rage ci gaban halayen oxyidative a cikin jiki da kuma rage matakin danniya.
(5). Inganta aikin enzyme antioxidant
Bincike ya nuna cewa Fisetin na iya inganta ayyukan enzyme masu mahimmanci na antioxidant, irin su superoxide dismutase (SOD) da glutathione peroxidase (GPx), don taimakawa kwayoyin halitta su jimre da damuwa na oxidative.
(6). M tasiri
Gabaɗaya, tsarin antioxidant naFisetin girmaya haɗa da ba da gudummawar electrons don kawar da radicals kyauta, kawar da oxidants masu aiki, hana ayyukan oxidase, da haɓaka ayyukan enzyme antioxidant, a tsakanin sauran hanyoyin, don aiwatar da tasirin antioxidant tare da kare sel daga lalacewar oxidative.
2. Sakamakon anti-mai kumburi na Fisetin
Fisetin kuma ana la'akari da shi yana da tasiri mai mahimmanci na maganin kumburi, yana taimakawa wajen rage halayen kumburi.
(1). Daidaita hanyoyin siginar kumburi
Fisetin yana haifar da sakamako mai cutarwa ta hanyar rinjayar ayyukan hanyoyin siginar kumburi da yawa. Zai iya daidaita NF-κ B. MAPK da STAT hanyoyin sigina sun hana bayyanar cututtuka masu alaƙa da kumburi, ta haka ne rage abin da ya faru da kuma dagewar halayen kumburi.
(2). Hana sakin masu shiga tsakani
Bincike ya nuna hakaPure Fisetin Fodana iya hana sakin masu shiga tsakani, irin su ƙwayar cuta necrosis factor- α (TNF) - α), Interleukin-1 β (IL-1) β) Kuma interleukin-6 (IL-6), da sauransu. muhimmiyar rawa a cikin amsawar kumburi, kuma hanawar Fisetin yana taimakawa wajen rage girman kumburi.
(3). Rage kunna ƙwayoyin kumburi
Fisetin na iya rage kunnawa da shigar da ƙwayoyin cuta masu kumburi (kamar macrophages, lymphocytes, da neutrophils), rage matakin da sel masu kumburi ke sakin masu shiga tsakani, don haka yana rage lalacewar nama ta hanyar halayen kumburi.
(4). Hana bayyanar cututtuka masu alaƙa da kumburi
Fisetin kuma na iya hana maganganun wasu sunadaran da ke da alaƙa da kumburi, irin su inducible nitric oxide synthase (iNOS) da cyclooxygenase-2 (COX-2), waɗanda ke taka muhimmiyar rawa a cikin tsarin kumburi. Ta hanyar hana maganganun su, Fisetin yana taimakawa wajen sarrafa amsawar kumburi.
(5). Haɗuwa da tasirin antioxidant da anti-mai kumburi
Ya kamata a lura cewa tasirin antioxidant na Fisetin shima yana ba da gudummawa ga tasirin sa na kumburi. Kayayyakin antioxidant na iya rage lalacewar danniya na oxidative zuwa sel, ta haka ne rage abubuwan da ba za a iya yin amfani da su ba na halayen kumburi da kuma kara rage girman kumburi.
3. Kariyar tsarin jin tsoro
(1). Kariyar Neuro
Bincike ya nuna hakaFisetin 98% zai iya inganta ci gaban neuronal da ci gaba, kuma yana da tasiri mai kariya akan ƙwayoyin cuta. Yana taimakawa wajen kula da yanayin lafiya na neurons, jinkirta jinkirin neuronal, kuma yana da tasiri mai kariya akan tsarin jin tsoro.
(2). Ka'idojin tafiyar da jijiya
Wasu nazarin sun nuna cewa Fisetin na iya taimakawa wajen inganta aikin tafiyar da jijiyoyi, inganta sakin neurotransmitters da watsa siginar jijiya, don haka inganta yanayin aiki na tsarin jin tsoro.
(3). Tsarin kwayoyin halitta neuroprotective
Fisetin na iya inganta karewa da gyaran tsarin jin tsoro ta hanyar daidaita maganganun wasu kwayoyin halitta na neuroprotective, irin su BDNF (kwakwalwa da aka samu neurotrophic factor).
Amincin shan Fisetin yau da kullun
(1). Binciken gwaji na dabba
Gwaje-gwajen dabbobi sun nuna cewa matsakaicin cin abinci na Fisetin yawanci yana da lafiya kuma ba a sami wani tasiri mai guba ba. Duk da haka, ya kamata a lura cewa sakamakon gwaje-gwajen dabba ba za a iya bayyana shi kai tsaye ga mutane ba.
(2). Kashi da bambancin mutum
Halin mutum ɗaya ga Fisetin na iya bambanta, kuma ana ba da shawarar bin shawarar shawarar masana'anta yayin shan Fisetin kuma a sa ido sosai kan halayen mutum ɗaya.
Kodayake Fisetin yana da fa'idodin kiwon lafiya da yawa, ana buƙatar ƙarin binciken kimiyya don tallafawa amincin shan Fisetin na yau da kullun. Masu saye yakamata suyi la'akari da cin abincin su na yau da kullun na Fisetin kuma su yanke shawara dangane da yanayin mutum. Ana ba da shawarar yin amfani da Fisetin a ƙarƙashin jagorancin likita mai ba da shawara don tabbatar da aminci da inganci.
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Lokacin aikawa: Maris 19-2024